Flavivirus NS1 and its potential in vaccine development
KL Carpio, ADT Barrett - Vaccines, 2021 - mdpi.com
The Flavivirus genus contains many important human pathogens, including dengue,
Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) …
Japanese encephalitis (JE), tick-borne encephalitis (TBE), West Nile (WN), yellow fever (YF) …
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate
The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the
development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are …
development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are …
The Japanese encephalitis antigenic complex viruses: from structure to immunity
In the last three decades, several flaviviruses of concern that belong to different antigenic
groups have expanded geographically. This has resulted in the presence of often more than …
groups have expanded geographically. This has resulted in the presence of often more than …
MVA-CoV2-S vaccine candidate neutralizes distinct variants of concern and protects against SARS-CoV-2 infection in hamsters
R Boudewijns, P Pérez, A Lázaro-Frías… - Frontiers in …, 2022 - frontiersin.org
To control the coronavirus disease 2019 (COVID-19) pandemic and the emergence of
different variants of concern (VoCs), novel vaccines against severe acute respiratory …
different variants of concern (VoCs), novel vaccines against severe acute respiratory …
Polyfunctional antibodies: a path towards precision vaccines for vulnerable populations
Vaccine efficacy determined within the controlled environment of a clinical trial is usually
substantially greater than real-world vaccine effectiveness. Typically, this results from …
substantially greater than real-world vaccine effectiveness. Typically, this results from …
Live-attenuated YF17D-vectored COVID-19 vaccine protects from lethal yellow fever virus infection in mouse and hamster models
Background The live-attenuated yellow fever vaccine YF17D holds great promise as
alternative viral vector vaccine platform, showcased by our previously presented potent …
alternative viral vector vaccine platform, showcased by our previously presented potent …
Multiplexed multicolor antiviral assay amenable for high-throughput research
To curb viral epidemics and pandemics, antiviral drugs are needed with activity against
entire genera or families of viruses. Here, we develop a cell-based multiplex antiviral assay …
entire genera or families of viruses. Here, we develop a cell-based multiplex antiviral assay …
A high-throughput yellow fever neutralization assay
M Rasulova, T Vercruysse, J Paulissen… - Microbiology …, 2022 - Am Soc Microbiol
Quick and accurate detection of neutralizing antibodies (nAbs) against yellow fever is
essential in serodiagnosis during outbreaks for surveillance and to evaluate vaccine efficacy …
essential in serodiagnosis during outbreaks for surveillance and to evaluate vaccine efficacy …
Rational development of live-attenuated Zika virus vaccines
A Adam, C Lee, T Wang - Pathogens, 2023 - mdpi.com
Zika virus (ZIKV), a re-emerging mosquito-borne flavivirus, has caused outbreaks in Africa,
Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the …
Asia, the Pacific, and, more recently, in the Americas. ZIKV has been associated with the …
Immunogenicity and protective ability of genotype I-based recombinant Japanese Encephalitis Virus (JEV) with attenuation mutations in E protein against genotype V …
S Tajima, S Taniguchi, E Nakayama, T Maeki, T Inagaki… - Vaccines, 2021 - mdpi.com
Genotype V (GV) Japanese encephalitis virus (JEV) has emerged in Korea and China since
2009. Recent findings suggest that current Japanese encephalitis (JE) vaccines may reduce …
2009. Recent findings suggest that current Japanese encephalitis (JE) vaccines may reduce …