Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Background Sarcopenia shares risk factors with various other age-related diseases. This
meta-analysis aimed to determine the prevalence of sarcopenia as a comorbid disease …

As the essential regulators of organ fibrosis, macrophages undergo marked phenotypic and
functional changes after organ injury. These changes in macrophage phenotype and …

Smoking is relevant to infectious diseases resulting in increased prevalence and mortality. In
this article, we aim to provide an overview of the effects of smoking in various infections and …

The same genetic variant found in different individuals can cause a range of diverse
phenotypes, from no discernible clinical phenotype to severe disease, even among related …

Neutrophils or polymorphonuclear leukocytes (PMN) are key participants in the innate
immune response for their ability to execute different effector functions. These cells express …

Chronic obstructive pulmonary disease (COPD) is a common respiratory disease that is
characterized by functional and structural alterations primarily caused by long-term …

Background & Aims Autophagy plays a crucial role in hepatic homeostasis and its
deregulation has been associated with chronic liver disease. However, the effect of …