Abstract The United States Food and Drug Administration (US FDA) has always been a
forerunner in drug evaluation and supervision. Over the past 31 years, 1050 drugs …

Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

Background: Publication of the 2015 American Thyroid Association (ATA) management
guidelines for adult patients with thyroid nodules and differentiated thyroid cancer was met …

Background Metastatic thyroid cancers that are refractory to radioiodine (iodine-131) are
associated with a poor prognosis. In mouse models of thyroid cancer, selective mitogen …

Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the publication of the American Thyroid …

Via its interaction in several pathways, normal thyroid function is important to maintain
normal reproduction. In both genders, changes in SHBG and sex steroids are a consistent …

Background: A risk-adapted approach to management of thyroid cancer requires risk
estimates that change over time based on response to therapy and the course of the …

Background It is not known whether low-dose radioiodine (1.1 GBq [30 mCi]) is as effective
as high-dose radioiodine (3.7 GBq [100 mCi]) for treating patients with differentiated thyroid …

Thyroid cancer is the fifth most common cancer in women in the USA, and an estimated over
62 000 new cases occurred in men and women in 2015. The incidence continues to rise …

Aim: The goal of this study was to estimate the cumulative activity of 131I to be administered
to patients with distant metastases from thyroid carcinoma. Methods: A total of 444 patients …