Spatial and temporal control of calcium (Ca 2+) levels is essential for the background
rhythms and responses of living cells to environmental stimuli. Whatever other regulators a …

Nuclear Ca2+ has emerged as one of the most potent mediators of the dialogue between
neuronal synapses and the nucleus that regulates heterochromatin states, transcription …

The remodelling of neuronal ionic homeostasis by altered channels and transporters is a
critical feature of the Alzheimer's disease (AD) pathogenesis. Different reports converge on …

Isolated exposure to intermittent hypoxia and permissive hypercapnia activates signaling
mechanisms that induce ultrastructural changes in mitochondria and endoplasmic reticulum …

Ca 2+ is a highly versatile intracellular signal that regulates many biological processes such
as cell death and proliferation. Broad Ca 2+-signaling machinery is used to assemble …

Nucleus is at the center stage of cellular drama orchestrated in the life of a cell and the
nucleoplasm is surrounded by a double membranous compartment constituting the Nuclear …

Disuse atrophy of skeletal muscle is associated with a severe imbalance in cellular Ca2+
homeostasis and marked increase in nuclear apoptosis. Nuclear Ca2+ is involved in the …

The suprachiasmatic nucleus (SCN) of the hypothalamus is the master circadian clock in
mammals. SCN neurons exhibit circadian Ca2+ rhythms in the cytosol, which is thought to …

Key components of endoplasmic reticulum (ER) Ca2+ release and store‐operated Ca2+
entry (SOCE) are likely expressed in all metazoan cells. Due to the complexity of canonical …

Jacob is a synapto-nuclear messenger protein that couples NMDAR activity to CREB-
dependent gene expression. In this study, we investigated the nuclear distribution of Jacob …