Alzheimer's disease (AD) is the most common cause of dementia. Despite many years of
research, very limited treatment options are available. Here we aim to establish a well …

Background: Cerebral Amyloid Angiopathy (CAA) disease course is highly variable even in
hereditary forms. Sex may be a possible modifying factor. We investigated biological sex …

Objective To investigate the multifactorial processes underlying cognitive aging based on
the hypothesis that multiple causal pathways and mechanisms (amyloid, vascular, and …

We assessed sex differences in amyloid-and tau-PET retention in 119 amyloid positive
patients with mild cognitive impairment or Alzheimer's disease (AD) dementia. Patients …

Increasing evidence supports that age, APOE and sex interact to modulate Alzheimer's
disease (AD) risk, however the underlying pathways are unclear. One way that AD risk …

Alzheimer's disease, characterized by neuroinflammation and beta-amyloid protein plaques,
is a memory-threatening neurodegenerative disease with no effective treatment. Here, the …

In this study, we aimed to assess whether women are able to withstand more tau before
exhibiting verbal memory impairment. Using data from 121 amyloid-β-positive Alzheimer's …

Epidemiological studies and clinical observations show evidence of sexual dimorphism in
brain responses to several neurological conditions. It is suggested that sex-related …

Highlights•AD disproportionally affects women in the development, progression and clinical
presentation of AD.•Our review summarized sex differences in biological change of AD from …

Abstract Purpose of Review The prevalence of Alzheimer's disease and related dementias is
greater in women compared to men. We provide a review of female sex-specific risk factors …