Alzheimer's disease (AD) is characterized by the progressive accumulation of amyloid-β and
hyperphosphorylated tau (pTau), which can spread throughout the brain via extracellular …

Abstract Purpose of Review The prevalence of Alzheimer's disease and related dementias is
greater in women compared to men. We provide a review of female sex-specific risk factors …

Introduction Downregulation of brain-derived neurotrophic factor (BDNF) and its cognate
neurotrophin receptor, TrkB, were observed during the progression of dementia, but whether …

We determined the prevalence of Alzheimer's disease (AD) pathological hallmarks, amyloid-
β and phosphorylated-Tau, in autopsied brains of 49 people with HIV (PWH)(ages: 50–68; …

Tau proteins accumulation and their spreading pattern were affected by gender in cognitive
impairment patients, especially in the progression of Alzheimer's disease (AD). However, it …

Background Many studies have reported that impaired gait precedes cognitive impairment in
older people. We aimed to characterise the time course of cognitive and motor decline in …

Alzheimer's disease (AD) is the most common cause of dementia. Despite many years of
research, very limited treatment options are available. Here we aim to establish a well …

To determine if sex differences in verbal memory in AD are related to differences in extent or
distribution of pathological tau, we studied 275 participants who were amyloid PET positive …

The study of sex differences in Alzheimer's disease is increasingly recognized as a key
priority in research and clinical development. People with Down syndrome represent the …

Purpose: Previously, sex and apolipoprotein E (APOE) genotype had distinct effects on the
cognitive trajectory across the Alzheimer's disease (AD) continuum. We therefore aimed to …