The diagnosis of pleural tuberculosis (plTB) by the analysis of pleural effusions (PEs) with
standard diagnostic tools is difficult. In routine clinical practice, the present authors …

Background Diagnosis and treatment of latent tuberculosis infection (LTBI) is a cornerstone
of tuberculosis (TB) control in the developed world. In the last century, the tuberculin skin test …

Background: Interferon-γ release assays for the diagnosis of infection with Mycobacterium
tuberculosis have been increasingly used in recent years and are endorsed by national …

Background Immunocompromised persons infected with Mycobacterium tuberculosis (MTB)
have increased risk of tuberculosis (TB) reactivation, but their management is hampered by …

The authors determined the positive predictive value (PPV) for progression to tuberculosis
(TB) of two interferon-γ release assays (IGRAs), QuantiFERON-TB® Gold In-tube (QFT-GIT) …

Background: The role of new T-cell–based blood tests for tuberculosis in the diagnosis of
active tuberculosis is unclear. Objective: To compare the performance of 2 interferon-γ …

Background Very little longitudinal information is available regarding the performance of T
cell-based tests for Mycobacterium tuberculosis infection. To address this deficiency, we …

For nearly a century, the tuberculin skin test was the only tool available for the detection of
latent tuberculosis infection. A recent breakthrough has been the development of T-cell …

IP-10 has potential as a diagnostic marker for infection with Mycobacteriumtuberculosis, with
comparable accuracy to QuantiFERON-TB Gold In-Tube test (QFT-IT). The aims were to …

Background Diagnosing extrapulmonary tuberculosis (E-TB) remains a challenge. A
recently developedMycobacterium tuberculosis–specific region of difference 1 gene-based …