This article provides an update about catecholamine metabolism, with emphasis on
correcting common misconceptions relevant to catecholamine systems in health and …

Hypoxia threatens brain function during the entire life-span starting from early fetal age up to
senescence. This review compares the short-term, long-term and life-spanning effects of …

Perinatal hypoxicischemic encephalopathy (HIE) is a significant cause of mortality and
morbidity in infants and young children. Therapeutic opportunities are very limited for …

In the premature infant, hypoxic-ischemic damage to the cerebral white matter
[periventricular leukomalacia (PVL)] is a common and leading cause of brain injury that often …

Neurotrophins activate several different intracellular signaling pathways that in some way
exert neuroprotective effects. In vitro studies of sympathetic and cerebellar granule neurons …

Brains from male cases with dyslexia show symmetry of the planum temporale and
predominantly leftsided cerebrocortical microdysgenesis. We now report on three women …

Birth asphyxia can cause moderate to severe brain injury. It is unclear to what degree
apoptotic or necrotic mechanisms of cell death account for damage after neonatal hypoxia …

Programmed cell death (apoptosis) is a normal process in the developing nervous system.
Recent data suggest that certain features seen in the process of programmed cell death may …

Perinatal asphyxia can result in neuronal injury with longterm neurological and behavioral
consequences. Although hypothermia may provide some modest benefit, the intervention …

Hypoxic–ischemic (HI) injury to the brain in the perinatal period often leads to significant
long-term neurological deficits. In a model of neonatal HI injury in postnatal day 7 rats, our …