Motor and non-motor circuit disturbances in early Parkinson disease: which happens first?
For the last two decades, pathogenic concepts in Parkinson disease (PD) have revolved
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
around the toxicity and spread of α-synuclein. Thus, α-synuclein would follow caudo-rostral …
Gastrointestinal dysfunction in Parkinson's disease
Our understanding of dysfunction of the gastrointestinal system in patients with Parkinson's
disease has increased substantially in the past decade. The entire gastrointestinal tract is …
disease has increased substantially in the past decade. The entire gastrointestinal tract is …
The O nset of N onmotor S ymptoms in P arkinson's disease (T he ONSET PD S tudy)
C Pont‐Sunyer, A Hotter, C Gaig, K Seppi… - Movement …, 2015 - Wiley Online Library
Nonmotor symptoms (NMS) in Parkinson's disease (PD) can precede onset of motor
symptoms. Relationship between premotor symptoms onset and motor features is limited …
symptoms. Relationship between premotor symptoms onset and motor features is limited …
Nonmotor features of Parkinson's disease subtypes
C Marras, KR Chaudhuri - Movement Disorders, 2016 - Wiley Online Library
Parkinson's disease is highly heterogeneous in early clinical features and later outcomes.
This makes classifying subgroups of PD relevant to clinical research and practice …
This makes classifying subgroups of PD relevant to clinical research and practice …
Premotor and nonmotor features of Parkinson's disease
JG Goldman, R Postuma - Current opinion in neurology, 2014 - journals.lww.com
Premotor and nonmotor features of Parkinson's disease : Current Opinion in Neurology
Premotor and nonmotor features of Parkinson's disease : Current Opinion in Neurology Log in or …
Premotor and nonmotor features of Parkinson's disease : Current Opinion in Neurology Log in or …
Health‐related quality of life in early Parkinson's disease: The impact of nonmotor symptoms
Nonmotor symptoms (NMS) are common in patients with established Parkinson's disease
(PD) and have a major impact upon quality of life. We investigated the significance of NMS …
(PD) and have a major impact upon quality of life. We investigated the significance of NMS …
The spectrum of nonmotor symptoms in early Parkinson disease
Objective: Nonmotor symptoms (NMS) are common in patients with established Parkinson
disease (PD) but their frequency in early PD has not been extensively studied. Our aim was …
disease (PD) but their frequency in early PD has not been extensively studied. Our aim was …
Association of autonomic dysfunction with disease progression and survival in Parkinson disease
Importance Evidence suggests that development of autonomic dysfunction (AutD) may
negatively affect disease course and survival in patients with synucleinopathies. However …
negatively affect disease course and survival in patients with synucleinopathies. However …
Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson's disease
B Müller, J Assmus, K Herlofson, JP Larsen… - Parkinsonism & related …, 2013 - Elsevier
Background The relative impact of motor-and non-motor symptoms on health-related quality
of life in early Parkinson's disease is poorly documented. Methods 188 patients with incident …
of life in early Parkinson's disease is poorly documented. Methods 188 patients with incident …
Pathological correlates of gastrointestinal dysfunction in Parkinson's disease
MG Cersosimo, EE Benarroch - Neurobiology of disease, 2012 - Elsevier
Gastrointestinal dysfunction is a prominent manifestation of Parkinson's disease (PD).
Gastrointestinal symptoms in PD include reduced salivation, dysphagia, impaired gastric …
Gastrointestinal symptoms in PD include reduced salivation, dysphagia, impaired gastric …