Monotherapy with a P2Y12 inhibitor or aspirin for secondary prevention in patients with established atherosclerosis: a systematic review and meta-analysis

M Chiarito, J Sanz-Sánchez, F Cannata, D Cao… - The Lancet, 2020 - thelancet.com
Background Antiplatelet therapy is recommended among patients with established
atherosclerosis. We compared monotherapy with a P2Y 12 inhibitor versus aspirin for …

Antithrombotic treatment after coronary artery bypass graft surgery: systematic review and network meta-analysis

K Solo, S Lavi, C Kabali, GN Levine, A Kulik… - bmj, 2019 - bmj.com
Objective To assess the effects of different oral antithrombotic drugs that prevent saphenous
vein graft failure in patients undergoing coronary artery bypass graft surgery. Design …

P2Y12 Inhibitor or Aspirin Monotherapy for Secondary Prevention of Coronary Events

F Gragnano, D Cao, L Pirondini, A Franzone… - Journal of the American …, 2023 - jacc.org
Background Aspirin is the only antiplatelet agent with a Class I recommendation for long-
term prevention of cardiovascular events in patients with coronary artery disease (CAD) …

Antithrombotic treatment strategies in patients with established coronary atherosclerotic disease

M Valgimigli, V Aboyans, D Angiolillo… - European Heart …, 2023 - academic.oup.com
Multiple guidelines and consensus papers have addressed the role of antithrombotic
strategies in patients with established coronary artery disease (CAD). Since evidence and …

Ticagrelor alone versus dual antiplatelet therapy from 1 month after drug-eluting coronary stenting

A Franzone, E McFadden, S Leonardi, R Piccolo… - Journal of the American …, 2019 - jacc.org
Abstract Background: The GLOBAL LEADERS (GLOBAL LEADERS: A Clinical Study
Comparing Two Forms of Anti-platelet Therapy After Stent Implantation) study randomly …

P2Y12 inhibitor versus aspirin monotherapy for secondary prevention of cardiovascular events: meta-analysis of randomized trials

D Aggarwal, K Bhatia, ZS Chunawala… - … heart journal open, 2022 - academic.oup.com
Aim To compare the efficacy and safety of P2Y12 inhibitor or aspirin monotherapy for
secondary prevention in patients with atherosclerotic cardiovascular disease (ASCVD) …

Ticagrelor: clinical development and future potential

NC Sanderson, WAE Parker… - Reviews in …, 2021 - eprints.whiterose.ac.uk
Platelets participate centrally in atherothrombosis, resulting in vessel occlusion and
ischaemia. Consequently, optimisation of antiplatelet regimens has the potential to further …

Antiplatelet therapy after coronary artery bypass surgery: five year follow-up of randomised DACAB trial

Y Zhu, W Zhang, A Dimagli, L Han, Z Cheng, J Mei… - bmj, 2024 - bmj.com
Objective To assess the effect of different antiplatelet strategies on clinical outcomes after
coronary artery bypass grafting. Design Five year follow-up of randomised Different …

Ticagrelor versus aspirin and vein graft patency after coronary bypass: a randomized trial

A Kulik, AM Abreu, V Boronat… - Journal of Cardiac …, 2022 - Wiley Online Library
Background Antiplatelet therapy prevents saphenous vein graft (SVG) occlusion and
improves outcomes after coronary artery bypass graft surgery (CABG). However, the optimal …

Review of the Ticagrelor Trials Evidence Base

GC Herron, ER Bates - Journal of the American Heart Association, 2024 - Am Heart Assoc
Ticagrelor is a platelet P2Y12 receptor inhibitor approved for use in patients with acute
coronary syndromes, coronary artery disease, and low‐moderate risk acute ischemic stroke …