[HTML][HTML] Complement activation in COVID-19 and targeted therapeutic options: a scoping review

EHT Lim, RBE van Amstel, VV de Boer, LA van Vught… - Blood Reviews, 2023 - Elsevier
Increasing evidence suggests that activation of the complement system plays a key role in
the pathogenesis and disease severity of Coronavirus disease 2019 (COVID-19). We used a …

[HTML][HTML] Complement and COVID-19: Three years on, what we know, what we don't know, and what we ought to know

WM Zelek, RA Harrison - Immunobiology, 2023 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus was identified in
China in 2019 as the causative agent of COVID-19, and quickly spread throughout the …

[HTML][HTML] Direct endothelial ENaC activation mitigates vasculopathy induced by SARS-CoV2 spike protein

MJ Romero, Q Yue, B Singla, J Hamacher… - Frontiers in …, 2023 - frontiersin.org
Introduction Although both COVID-19 and non-COVID-19 ARDS can be accompanied by
significantly increased levels of circulating cytokines, the former significantly differs from the …

Effect of coronaviruses on blood vessel permeability: potential therapeutic targets

NR Machado, KT Dias, BFS Cortes… - Therapeutic …, 2023 - journals.sagepub.com
Coronavirus-induced diseases have afflicted humanity for several decades. This scenario
was aggravated by the emergence of the coronavirus disease 2019 (named COVID-19) in …

[HTML][HTML] Evaluation of bovine coronavirus in Korean native calves challenged through different inoculation routes

HC Cho, Y Kim, YI Cho, J Park, KS Choi - Veterinary Research, 2024 - ncbi.nlm.nih.gov
Bovine coronavirus (BCoV) is a pneumoenteric virus that can infect the digestive and
respiratory tracts of cattle, resulting in economic losses. Despite its significance, information …

[HTML][HTML] Hydrogen Sulfide Ameliorates SARS-CoV-2-Associated Lung Endothelial Barrier Disruption

O Escaffre, P Szaniszlo, G Törő, CL Vilas, BJ Servantes… - Biomedicines, 2023 - mdpi.com
Recent studies have confirmed that lung microvascular endothelial injury plays a critical role
in the pathophysiology of COVID-19. Our group and others have demonstrated the …

[HTML][HTML] Modulation of expression of Connexins 37, 40 and 43 in endothelial cells in culture

W Zhuang, NGA Mitrou, S Kulak… - Frontiers in Network …, 2024 - frontiersin.org
Connexin (Cx) 37, 40, and 43 are implicated in vascular function, specifically in the electrical
coupling of endothelial cells and vascular smooth-muscle cells. In the present study, we …

Plasma of COVID-19 patients does not alter electrical resistance of human endothelial blood-brain barrier in vitro

A Pociūtė, K Kriaučiūnaitė, A Kaušylė, B Zablockienė… - Function, 2024 - academic.oup.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 instigated the most serious global health crisis. Clinical …