Diabetic macular edema: current understanding, molecular mechanisms and therapeutic implications

J Zhang, J Zhang, C Zhang, J Zhang, L Gu, D Luo… - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), with increasing incidence, is the major cause of vision loss and
blindness worldwide in working-age adults. Diabetic macular edema (DME) remains the …

[HTML][HTML] Optical coherence tomography angiography

RF Spaide, JG Fujimoto, NK Waheed, SR Sadda… - Progress in retinal and …, 2018 - Elsevier
Optical coherence tomography (OCT) was one of the biggest advances in ophthalmic
imaging. Building on that platform, OCT angiography (OCTA) provides depth resolved …

[HTML][HTML] Mechanisms of macular edema: beyond the surface

A Daruich, A Matet, A Moulin, L Kowalczuk… - Progress in retinal and …, 2018 - Elsevier
Macular edema consists of intra-or subretinal fluid accumulation in the macular region. It
occurs during the course of numerous retinal disorders and can cause severe impairment of …

OCT angiography metrics predict progression of diabetic retinopathy and development of diabetic macular edema: a prospective study

Z Sun, F Tang, R Wong, J Lok, SKH Szeto, JCK Chan… - Ophthalmology, 2019 - Elsevier
Purpose To prospectively determine the relationship of OCT angiography (OCTA) metrics to
diabetic retinopathy (DR) progression and development of diabetic macular edema (DME) …

Bacillary layer detachment: multimodal imaging and histologic evidence of a novel optical coherence tomography terminology: literature review and proposed theory

P Ramtohul, M Engelbert, A Malclès, E Gigon… - Retina, 2021 - journals.lww.com
Purpose: To clarify the histologic basis of bacillary layer detachment (BALAD) through a
review of the current literature and an analysis of retinal imaging. Methods: The literature for …

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis

A Petzold, LJ Balcer, PA Calabresi, F Costello… - The Lancet …, 2017 - thelancet.com
Background Structural retinal imaging biomarkers are important for early recognition and
monitoring of inflammation and neurodegeneration in multiple sclerosis. With the …

[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

Diabetic macular edema with neuroretinal detachment: OCT and OCT-angiography biomarkers of treatment response to anti-VEGF and steroids

S Vujosevic, C Toma, E Villani, A Muraca, E Torti… - Acta …, 2020 - Springer
Purpose To assess and compare early changes in neuroinflammatory and vascular
parameters in diabetic macular edema (DME) with subfoveal neuroretinal detachment …

The role of intravitreal corticosteroids in the treatment of DME: predictive OCT biomarkers

MR Munk, GM Somfai, MD de Smet, G Donati… - International journal of …, 2022 - mdpi.com
This work aims to summarize predictive biomarkers to guide treatment choice in DME.
Intravitreal anti-VEGF is considered the gold standard treatment for centers involving DME …

Cystoid macular edema related to cataract surgery and topical prostaglandin analogs: mechanism, diagnosis, and management

G Holló, T Aung, LB Cantor, M Aihara - Survey of Ophthalmology, 2020 - Elsevier
Cystoid macular edema (CME) is a form of macular retina thickening that is characterized by
the appearance of cystic fluid-filled intraretinal spaces. It has classically been diagnosed …