The modulatory effect of high salt on immune cells and related diseases

X Li, A Alu, Y Wei, X Wei, M Luo - Cell proliferation, 2022 - Wiley Online Library
Background The adverse effect of excessive salt intake has been recognized in decades.
Researchers have mainly focused on the association between salt intake and hypertension …

[HTML][HTML] Neuropathic pain in multiple sclerosis and its animal models: focus on mechanisms, knowledge gaps and future directions

E Mirabelli, S Elkabes - Frontiers in Neurology, 2021 - frontiersin.org
Multiple sclerosis (MS) is a multifaceted, complex and chronic neurological disease that
leads to motor, sensory and cognitive deficits. MS symptoms are unpredictable and …

Synthesis and comprehensive in vivo activity profiling of olean-12-en-28-ol, 3β-pentacosanoate in experimental autoimmune encephalomyelitis: a natural …

H Senol, O Ozgun-Acar, A Dag, A Eken… - Journal of Natural …, 2023 - ACS Publications
Multiple sclerosis (MS) treatment has received much attention, yet there is still no certain
cure. We herein investigate the therapeutic effect of olean-12-en-28-ol, 3β-pentacosanoate …

[HTML][HTML] Neurological benefits, clinical challenges, and neuropathologic promise of medical marijuana: A systematic review of cannabinoid effects in multiple sclerosis …

V Longoria, H Parcel, B Toma, A Minhas, R Zeine - Biomedicines, 2022 - mdpi.com
Despite current therapeutic strategies for immunomodulation and relief of symptoms in
multiple sclerosis (MS), remyelination falls short due to dynamic neuropathologic …

[HTML][HTML] Delimiting MOGAD as a disease entity using translational imaging

FC Oertel, M Hastermann, F Paul - Frontiers in Neurology, 2023 - frontiersin.org
The first formal consensus diagnostic criteria for myelin oligodendrocyte glycoprotein
antibody-associated disease (MOGAD) were recently proposed. Yet, the distinction of …

[HTML][HTML] New insights into risk genes and their candidates in multiple sclerosis

R Shirai, J Yamauchi - Neurology International, 2022 - mdpi.com
Oligodendrocytes are central nervous system glial cells that wrap neuronal axons with their
differentiated myelin membranes as biological insulators. There has recently been an …

[PDF][PDF] 阿托伐他汀对自身免疫性脑脊髓炎小鼠髓鞘修复及RhoA/Rock1 通路的影响

张沁丽, 王玉芬, 刘红, 刘博雯 - 中国比较医学杂志, 2022 - zgbjyx.cnjournals.com
目的探讨阿托伐他汀对自身免疫性脑脊髓炎(EAE) 小鼠髓鞘修复及RhoA/Rock1 通路的影响.
方法采用MOG35-55 免疫建立EAE 小鼠模型, 小鼠随机分为空白组, 模型组, 阿托伐他汀组 …

Mechanisms of occurrence and chronicity of neuropathic pain in multiple sclerosis in clinical and experimental conditions| Український Медичний Часопис

OO Nefedov, OI Kalbus - Mechanisms of occurrence and chronicity of …, 2022 - umj.com.ua
Резюме Multiple sclerosis (MS) is a multifaceted, complex chronic neurological disease that
leads to motor, sensory and cognitive impairment. The symptoms of MS are unpredictable …

Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis

A Muñoz-Jurado, BM Escribano… - Methods in cell …, 2024 - pubmed.ncbi.nlm.nih.gov
Multiple sclerosis (MS) is a very complex and heterogeneous disease, with an unknown
etiology and which, currently, remains incurable. For this reason, animal models are crucial …

Linking multiple sclerosis genetic risk variants to gene expression data

D Kurtoić - 2022 - mediatum.ub.tum.de
Research on multiple sclerosis still lacks more precise insights into genetically determined
mechanisms of disease susceptibility. Here, it was found that mice that spontaneously …