The rise of drug-resistance has made the deserted clinical requirement to improve of new
classes of antibiotics agents. The development of antibacterial agents with the novel method …

The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …

Cobalt complexes of chiral pyrox ligands catalyzed enantioselective reductive couplings of
nonconjugated iododienes with aryl iodides or alkenyl bromides. The reaction enabled …

Reaction rate acceleration using green methods is an intriguing area of research for
chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of …

With the increasing number of cases of inactive and drug-resistance tuberculosis, there is an
urgent need to develop new potent molecules set for fighting this brutal disease. Medicinal …

Despite diversity in reaction mechanisms, the palladium-catalyzed cyclization of 1, 6-enyne
generally proceeds in a 5-exo manner. Herein, we report the development of a Pd (0) …

This study reports the formation of 5-FU co-crystals with four different pharmacologically safe
co-formers; Urea, Thiourea, Acetanilide and Aspirin using methanol as a solvent. Two …

A series of novel substituted azepines (2–7) was synthesized using both traditional and
ultrasonic techniques. The efficiency of the reaction rate and yield was improved by …

Abstract β-Carboline alkaloids are an eminent class of nitrogen-based natural alkaloids and
therapeutic molecules which exert various pharmacological activities through diverse …

A novel catalyst-controlled cycloisomerization/[4+ 3] cycloaddition sequence of readily
available acyclic enyne-amides and crotonate-derived sulfur ylides is reported. This strategy …