[PDF][PDF] 人细胞色素P450 1A2 的发育变化及基因多态性的临床意义

高向波, 江周虹, 王玉梅, 余露山… - 中国药学 …, 2019 - journal11.magtechjournal.com
综述发育过程中细胞色素P450 1A2 (cytochrome P450 1A2, CYP1A2) 代谢酶的变化及基因多
态性对临床用药的影响. 通过查阅国内外相关文献, 进行分析, 归纳和总结. CYP1A2 …

Chromatographic techniques in analysis of cyclooxygenase-2 inhibitors in drugs and biological samples

M Starek, M Dąbrowska - Central European Journal of Chemistry, 2012 - Springer
Non-steroidal anti-inflammatory drugs, as a therapeutic class, are among the most often
used active pharmaceutical ingredients in heath care in the world. They are mostly available …

[HTML][HTML] Cytochrome P450-mediated drug interactions affecting lidocaine

M Isohanni - 2009 - helda.helsinki.fi
Lidocaine is a widely used local anaesthetic agent that also has anti-arrhythmic effects. It is
classified as a type Ib anti-arrhythmic agent and is used to treat ventricular tachycardia or …

[HTML][HTML] Коррекция экстрапирамидных побочных эффектов антипсихотической терапии у больных шизофренией на этапе амбулаторной психиатрической …

ТМ Полозова, ДИ Малин - Социальная и клиническая …, 2011 - cyberleninka.ru
В работе представлены данные по оценки распространенности и описанию
клинических проявлений экстрапирамидных нейролептических синдромов у 272 …

Spasticity due to disease of the spinal cord: pathophysiology, epidemiology and treatment

HW Walker, AJ Hon, S Kirshblum - Spasticity: Diagnosis and …, 2016 - books.google.com
Spasticity is a common sensorimotor symptom complex commonly experienced by
individuals sustaining spinal cord injury (SCI) with upper motor neuron (UMN) involvement …

Drug‐Metabolizing Enzymes, Transporters, and Drug–Drug Interactions

SW Louie, M Shou - … in Drug Metabolism and Disposition: Basic …, 2011 - Wiley Online Library
4.2. 2 UDP–Glucuronosyltransferases 4.2. 3 Sulfotransferases 4.2. 4 Glutathione-S-
Transferases 4.2. 5 Regulation of Human CYPs 4.3 Metabolism-Based DDIs 4.3. 1 Reaction …

液相色谱-串联质谱法测定人血浆中替扎尼定

万咪咪, 詹燕, 陈笑艳, 张逸凡, 钟大放 - 药物分析杂志, 2011 - cqvip.com
目的: 建立灵敏的液相色谱-串联质谱法测定人血浆中替扎尼定的浓度. 方法:
血浆样品碱化后经乙醚液-液萃取, 以甲醇-10 mmo· lL-1 醋酸铵-甲酸(55∶ 45∶ 0.1, v/v/v) …

Anti-inflammatory and antipyretic analgesics and drugs used in gout

JK Aronson - Side Effects of Drugs Annual, 2009 - Elsevier
Publisher Summary This chapter reviews anti-inflammatory and antipyretic analgesics and
drugs used in gout. The association between paracetamol and upper gastrointestinal …

Lower metabolic clearance of tizanidine in Japanese subjects.

K Momo, M Homma, Y Kohda - International journal of clinical …, 2013 - europepmc.org
Our aim was to determine whether metabolic clearance, renal clearance, or both elimination
pathways contribute to ethnic differences in tizanidine clearance, which is~ 2-fold higher in …

[HTML][HTML] Изоформа CYP1A2, как составная часть суперсемейства цитохрома P450

ЯГ Новицкая, ВП Жердев, АО Виглинская… - Фармакокинетика и …, 2014 - cyberleninka.ru
Описана роль цитохрома Р450 и его изоформы CYP1A2 в метаболизме кофеина.
Представлены данные о фармакокинетике кофеина у человека и лабораторных …