Cotton bollworm (Helicoverpa armigera) is one of the most serious insect pests of cotton.
Transgenic cotton expressing Cry toxins derived from a soil bacterium, Bacillus thuringiensis …

The striped stem borer, Chilo suppressalis, is a major target pest of transgenic rice
expressing the Cry1Ab protein from the bacterium Bacillus thuringiensis (Bt) in China …

Cultured cells are a very powerful tool for investigating biological events in vitro; therefore,
cell lines have been established not only in model insect species, but also in non-model …

The midgut of most insects is lined with a semipermeable acellular tube, the peritrophic
matrix (PM), composed of chitin and proteins. Although various genes encoding PM proteins …

The insecticidal Cry proteins produced by Bacillus thuringiensis strains are pore-forming
toxins (PFTs) that bind to the midgut brush border membrane and cause extensive damage …

Aminopeptidases N (APNs), the receptors of Bacillus thuringiensis (Bt) toxin in the
lepidopteran midgut, are involved in the Bt pathogen infection mechanism. In the present …

Background RNA interference (RNAi) leads to sequence specific knock-down of gene
expression and has emerged as an important tool to analyse gene functions, pathway …

Aminopeptidase N (APN) isoforms in insects have been documented to be involved in the
mode of action of insecticidal crystal proteins (Cry) from Bacillus thuringiensis. Here we …

Protecting crops against insect pests is a major focus area in crop protection. Over the past
two decades, biotechnological interventions, especially Bt proteins, have been successfully …

RNAi is a gene-silencing mechanism conserved in the vast majority of eukaryotes. It is
widely used to study gene function in animals due to the ease of eliciting gene knockdown …