Procalcitonin for the diagnosis of postoperative bacterial infection after adult cardiac surgery: a systematic review and meta-analysis

D Nicolotti, S Grossi, V Palermo, F Pontone… - Critical Care, 2024 - Springer
Background and aims Patients undergoing cardiac surgery are subject to infectious
complications that adversely affect outcomes. Rapid identification is essential for adequate …

When to Stop Antibiotics in the Critically Ill?

ND Nielsen, JT Dean III, EA Shald, A Conway Morris… - Antibiotics, 2024 - mdpi.com
Over the past century, antibiotic usage has skyrocketed in the treatment of critically ill
patients. There have been increasing calls to establish guidelines for appropriate treatment …

Therapeutic Drug Monitoring and Biomarkers; towards Better Dosing of Antimicrobial Therapy

E Wehbe, AE Patanwala, CY Lu, HY Kim, SL Stocker… - Pharmaceutics, 2024 - mdpi.com
Due to variability in pharmacokinetics and pharmacodynamics, clinical outcomes of
antimicrobial drug therapy vary between patients. As such, personalised medication …

Comparative Impact of an Optimized PK/PD Target Attainment of Piperacillin-Tazobactam vs. Meropenem on the Trend over Time of SOFA Score and Inflammatory …

M Gatti, M Rinaldi, T Tonetti, A Siniscalchi, P Viale… - Antibiotics, 2024 - mdpi.com
(1) Background: The advantage of using carbapenems over beta-lactam/beta-lactamase
inhibitor combinations in critically ill septic patients still remains a debated issue. We aimed …

Major burns in adults: a practice review

A Gwyn-Jones, T Afolabi, S Bonney… - Emergency Medicine …, 2024 - emj.bmj.com
There are approximately 180 000 deaths per year from thermal burn injury worldwide. Most
burn injuries can be treated in local hospitals but 6.5% require specialist burn care. The …

Systemic Inflammatory Response Syndrome After MitraClip

C Mannina, A Kini, S Lerakis - Annals of Internal Medicine: Clinical …, 2024 - acpjournals.org
An octogenarian patient with multiple comorbid conditions, including heart failure with
preserved ejection fraction and primary mitral valve regurgitation, presented with shortness …