Levodopa-induced dyskinesia in Parkinson's disease: pathogenesis and emerging treatment strategies
The most commonly used treatment for Parkinson's disease (PD) is levodopa, prescribed in
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …
conjunction with carbidopa. Virtually all patients with PD undergo dopamine replacement …
Current understanding of the molecular mechanisms in Parkinson's disease: Targets for potential treatments
P Maiti, J Manna, GL Dunbar - Translational neurodegeneration, 2017 - Springer
Gradual degeneration and loss of dopaminergic neurons in the substantia nigra, pars
compacta and subsequent reduction of dopamine levels in striatum are associated with …
compacta and subsequent reduction of dopamine levels in striatum are associated with …
[HTML][HTML] Parkinson's disease and its management: part 1: disease entity, risk factors, pathophysiology, clinical presentation, and diagnosis
G DeMaagd, A Philip - Pharmacy and therapeutics, 2015 - ncbi.nlm.nih.gov
Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …
Levodopa‐induced dyskinesia in Parkinson disease: current and evolving concepts
Levodopa‐induced dyskinesia is a common complication in Parkinson disease. Pathogenic
mechanisms include phasic stimulation of dopamine receptors, nonphysiological levodopa …
mechanisms include phasic stimulation of dopamine receptors, nonphysiological levodopa …
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease
Involuntary movements, or dyskinesia, represent a debilitating complication of levodopa (L-
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
dopa) therapy for Parkinson's disease (PD). L-dopa-induced dyskinesia (LID) are ultimately …
The Movement Disorder Society Evidence‐Based Medicine Review Update: Treatments for the motor symptoms of Parkinson's disease
The objective was to update previous evidence‐based medicine reviews of treatments for
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …
motor symptoms of Parkinson's disease published between 2002 and 2005. Level I …
The scientific and clinical basis for the treatment of Parkinson disease (2009)
CW Olanow, MB Stern, K Sethi - Neurology, 2009 - AAN Enterprises
Parkinson disease (PD) is an age-related neurodegenerative disorder that affects as many
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
as 1–2% of persons aged 60 years and older. With the aging of the population, the …
The pharmacology of L-DOPA-induced dyskinesia in Parkinson's disease
l-3, 4-Dihydroxyphenylalanine (l-DOPA) remains the most effective symptomatic treatment of
Parkinson's disease (PD). However, long-term administration of l-DOPA is marred by the …
Parkinson's disease (PD). However, long-term administration of l-DOPA is marred by the …
Practice Parameter: Treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review):[RETIRED] Report of the Quality Standards …
R Pahwa, SA Factor, KE Lyons, WG Ondo, G Gronseth… - Neurology, 2006 - AAN Enterprises
Objective: To make evidence-based treatment recommendations for the medical and
surgical treatment of patients with Parkinson disease (PD) with levodopa-induced motor …
surgical treatment of patients with Parkinson disease (PD) with levodopa-induced motor …
Levodopa‐induced dyskinesias
G Fabbrini, JM Brotchie, F Grandas… - … : official journal of the …, 2007 - Wiley Online Library
Levodopa‐induced dyskinesias (LID) are common and difficult to treat. This review focuses
on three issues related to LID: clinical features, classification and rating, pathophysiology …
on three issues related to LID: clinical features, classification and rating, pathophysiology …