Considerable evidence implies that an enteroviral infection may accelerate or precipitate
type 1 diabetes (T1D) in some individuals. However, causality is not proven. We present and …

Type 1 diabetes mellitus (T1DM) is a chronic disease resulting from destruction of insulin-
producing pancreatic β cells. Genetic and environmental factors contribute to T1DM onset …

The great preclinical promise of the pancreatic endoplasmic reticulum kinase (PERK)
inhibitors in neurodegenerative disorders and cancers is marred by pancreatic injury and …

Increased serum levels of IL-15 are reported in type 1 diabetes (T1D). Here we report
elevated serum soluble IL-15Rα levels in human T1D. To investigate the role of IL-15/IL …

Abstract Aim Type 1 diabetes (T1D) is a chronic autoimmune disease leading to progressive
loss of pancreatic beta cells. Interferon (IFN)‐α plays a critical role in the crosstalk between …

Type 1 diabetes mellitus is an autoimmune disease characterized by the destruction of the
insulin-producing islet β cells. It is likely that several genetic and environmental factors …

Type 1 diabetes (T1D) is caused by autoimmune destruction of the insulin-producing β cells
in the pancreatic islets, which are essentially mini-organs embedded in exocrine tissue …

Type 1 diabetes mellitus (T1D) is an autoimmune illness that affects millions of patients
worldwide. The main characteristic of this disease is the destruction of pancreatic insulin …

Previous studies have shown that enteroviral RNA can be detected in blood at the onset of
type 1 diabetes (T1D). The infection may play a role in triggering T1D and genetic host …

A hallmark of patients with autoimmune polyendocrine syndrome type 1 (APS-1) is
serological neutralizing autoantibodies against type 1 interferons (IFN-I). The presence of …