Therapeutic DNAzymes have unceasingly intrigued the scientific community owing to their
prosperous gene regulation capability. The efficacy of DNAzymes against many types of …

The leading cause of death in the world, cardiovascular disease (CVD), remains a
formidable condition for researchers, clinicians and patients alike. CVD comprises a broad …

Despite the great efforts of using DNAzyme for gene therapy, its clinical success is limited by
the lack of simple delivery systems and limited anticancer efficacy. Here, we develop a …

Use of gold nanoparticles (GNPs) in medicine is an emerging field of translational research
with vast clinical implications and exciting therapeutic potential. However, the safety of using …

Although chemotherapy is one of the most widely used cancer treatments, there are serious
side effects, drug resistance, and secondary metastasis. To address these problems, herein …

Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …

It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Organ ischemia with inadequate oxygen supply followed by reperfusion (which initiates a
complex of inflammatory responses and oxidative stress) occurs in different clinical …

Over the past few decades, DNA nanotechnology engenders a vast variety of programmable
nanostructures utilizing Watson–Crick base pairing. Due to their precise engineering …

The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …