[HTML][HTML] Identification of a gene signature for different stages of breast cancer development that could be used for early diagnosis and specific therapy
C Kothari, G Ouellette, Y Labrie, S Jacob, C Diorio… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Breast cancer (BC) is a heterogeneous disease where the survival rate of patients
decreases with progression of the disease. BC usually has a linear progression, classified …
decreases with progression of the disease. BC usually has a linear progression, classified …
[HTML][HTML] Genome-Wide Gene Expression Analyses of BRCA1- and BRCA2-Associated Breast and Ovarian Tumours
GAR Wiggins, LC Walker, JF Pearson - Cancers, 2020 - mdpi.com
Simple Summary Variants in the breast cancer susceptibility genes BRCA1 and BRCA2
increase the risk of developing breast and ovarian cancers. Over the past two decades …
increase the risk of developing breast and ovarian cancers. Over the past two decades …
Tree-weighting for multi-study ensemble learners
M Ramchandran, P Patil… - Pacific Symposium on …, 2019 - World Scientific
Multi-study learning uses multiple training studies, separately trains classifiers on each, and
forms an ensemble with weights rewarding members with better cross-study prediction …
forms an ensemble with weights rewarding members with better cross-study prediction …
[HTML][HTML] TBC1D9: an important modulator of tumorigenesis in breast cancer
C Kothari, A Clemenceau, G Ouellette, K Ennour-Idrissi… - Cancers, 2021 - mdpi.com
Simple Summary Triple negative breast cancer (TNBC) lacks the expression of hormonal
receptors estrogen and progesterone along with the over-expression of human epithelial …
receptors estrogen and progesterone along with the over-expression of human epithelial …
[HTML][HTML] Is carboxypeptidase B1 a prognostic marker for ductal carcinoma in situ?
C Kothari, A Clemenceau, G Ouellette, K Ennour-Idrissi… - Cancers, 2021 - mdpi.com
Simple Summary Ductal carcinoma in situ (DCIS) is an early-stage breast cancer (BC), in
which tumor cells are growing in a localized duct of the mammary gland. DCIS is considered …
which tumor cells are growing in a localized duct of the mammary gland. DCIS is considered …
[HTML][HTML] An isoform of AIF1 involved in breast cancer
FA Slim, G Ouellette, K Ennour-Idrissi, S Jacob… - Cancer Cell …, 2018 - Springer
Background Inflammation is a major player in breast cancer (BC) progression. Allograft-
inflammatory factor-1 (AIF1) is a crucial mediator in the inflammatory response. AIF1 …
inflammatory factor-1 (AIF1) is a crucial mediator in the inflammatory response. AIF1 …
[HTML][HTML] Increased gene expression variability in BRCA1-associated and basal-like breast tumours
Purpose Inherited variants in the cancer susceptibility genes, BRCA1 and BRCA2 account
for up to 5% of breast cancers. Multiple gene expression studies have analysed gene …
for up to 5% of breast cancers. Multiple gene expression studies have analysed gene …
Gene signatures of breast cancer development and the potential for novel targeted treatments
C Kothari, C Diorio, F Durocher - Pharmacogenomics, 2020 - Taylor & Francis
Breast cancer (BC) is a heterogeneous disease; a single tumor can be classified differently
according to its histological grade, stage, appearance and expression of receptors …
according to its histological grade, stage, appearance and expression of receptors …
[HTML][HTML] Bayesian combinatorial MultiStudy factor analysis
Mutations in the BRCA1 and BRCA2 genes are known to be highly associated with breast
cancer. Identifying both shared and unique transcript expression patterns in blood samples …
cancer. Identifying both shared and unique transcript expression patterns in blood samples …
Probabilistic approaches to multi-study genomic matrix decompositions and single-cell RNA-sequencing analysis
IN Grabski - 2023 - search.proquest.com
Analyzing genomic data yields critical insights into important biological and clinical
questions, but can be challenging due to noise, sparsity, and systematic sources of …
questions, but can be challenging due to noise, sparsity, and systematic sources of …