Safety of aggressive lipid management

MH Davidson, JG Robinson - Journal of the American College of …, 2007 - jacc.org
Data from recent clinical trials of high-versus moderate-dose statin therapy support the
recommendation to achieve a low-density lipoprotein (LDL)< 100 mg/dl in high-risk patients …

Comparative efficacy of the addition of ezetimibe to statin vs statin titration in patients with hypercholesterolaemia: systematic review and meta-analysis

DP Mikhailidis, RW Lawson… - … medical research and …, 2011 - Taylor & Francis
Objective: To systematically review and analyse evidence for cholesterol-lowering efficacy of
at least 4 weeks of add-on ezetimibe vs doubling statin dose, in adults with primary …

[图书][B] Hyperlipidaemia 3Ed: diagnosis and management

P Durrington - 2007 - books.google.com
The third edition of this well-received text provides a state-of-the-art treatise on modern
clinical practice relating to hyperlipidaemia and lipoprotein disorders, conditions responsible …

Meta-analysis of the cholesterol-lowering effect of ezetimibe added to ongoing statin therapy

DP Mikhailidis, GC Sibbring… - … medical research and …, 2007 - Taylor & Francis
Objective: To review and analyse the evidence for the cholesterol-lowering effect of
ezetimibe in adult patients with hypercholesterolaemia who are not at low-density …

Ezetimibe/simvastatin vs atorvastatin in patients with type 2 diabetes mellitus and hypercholesterolemia: the VYTAL study

RB Goldberg, JR Guyton, T Mazzone… - Mayo Clinic …, 2006 - Elsevier
OBJECTIVE To compare the efficacy and safety of the recommended usual starting and next
highest doses of ezetimibe/simvastatin and atorvastatin in patients with type 2 diabetes …

Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients

AL Catapano, MH Davidson… - … medical research and …, 2006 - Taylor & Francis
Objective: To assess the lipid-altering efficacy and safety of ezetimibe/simvastatin single
tablet product compared with rosuvastatin at the approved usual starting, next highest, and …

Comparison of the effects of simvastatin vs. rosuvastatin vs. simvastatin/ezetimibe on parameters of insulin resistance

E Moutzouri, E Liberopoulos… - … journal of clinical …, 2011 - Wiley Online Library
Background: Statin treatment may be associated with adverse effects on glucose
metabolism. Whether this is a class effect is not known. In contrast, ezetimibe monotherapy …

[HTML][HTML] Changes in lipoproteins associated with lipid-lowering and antiplatelet strategies in patients with acute myocardial infarction

Z Lotfollahi, APQ Mello, FAH Fonseca, LO Machado… - PloS one, 2022 - journals.plos.org
Background Despite lipid-lowering and antiplatelet therapy, the pattern of residual
lipoproteins seems relevant to long-term cardiovascular outcomes. This study aims to …

Lipid-lowering drugs acting at the level of the gastrointestinal tract

TD Filippatos, DP Mikhailidis - Current pharmaceutical design, 2009 - ingentaconnect.com
This review considers the hypolipidaemic drugs that act on the gastrointestinal (GI) tract. We
searched PubMed up to April 2008 and included randomized controlled trials, original …

Pleiotropic effects of ezetimibe: do they really exist?

M Kalogirou, V Tsimihodimos, M Elisaf - European journal of pharmacology, 2010 - Elsevier
Ezetimibe represents a new lipid lowering agent which inhibits cholesterol absorption. It
effectively reduces low-density lipoprotein cholesterol when administered either alone or in …