Immunological impact of cytokines on the chikungunya virus pathophysiology: A literature narrative review

JAL Nunes, JR Sousa, VC Smith… - Reviews in Medical …, 2023 - Wiley Online Library
The chikungunya virus (CHIKV) is a member of the genus Alphavirus, family Togaviridae.
CHIKV causes an acute systemic febrile condition, accompanied by severe polyarthralgia …

The causes and long-term consequences of viral encephalitis

K Bohmwald, CA Andrade, NMS Gálvez… - Frontiers in Cellular …, 2021 - frontiersin.org
Reports regarding brain inflammation, known as encephalitis, have shown an increasing
frequency during the past years. Encephalitis is a relevant concern to public health due to its …

[PDF][PDF] Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses

G Garcia, JI Irudayam, AV Jeyachandran, S Dubey… - Cell Reports …, 2023 - cell.com
RNA viruses continue to remain a threat for potential pandemics due to their rapid evolution.
Potentiating host antiviral pathways to prevent or limit viral infections is a promising strategy …

The 8-bromobaicalein alleviated chikungunya-induced musculoskeletal inflammation and reduced the viral load in healthy adult mice

V Cao, N Loeanurit, K Hengphasatporn… - Emerging Microbes & …, 2023 - Taylor & Francis
Chikungunya virus is a re-emerging arbovirus that has caused epidemic outbreaks in recent
decades. Patients in older age groups with high viral load and severe immunologic …

[HTML][HTML] Development and application of treatment for Chikungunya fever

EM Millsapps, EC Underwood… - Research and Reports in …, 2022 - ncbi.nlm.nih.gov
The development and application of treatment for Chikungunya fever (CHIKF) remains
complicated as there is no current standard treatment and many barriers to research exist …

Increased circulating levels of High Mobility Group Box 1 (HMGB1) in acute-phase Chikungunya virus infection: Potential disease biomarker

DCP Rocha, TMA Souza, PCG Nunes… - Journal of Clinical …, 2022 - Elsevier
Background Chikungunya virus (CHIKV) causes a febrile syndrome with intense and
debilitating arthralgia that can persist for several months or years after complete virus …

Chikungunya Immunopathology as It Presents in Different Organ Systems

EM Traverse, EM Millsapps, EC Underwood… - Viruses, 2022 - mdpi.com
Chikungunya virus (CHIKV) is currently an urgent public health problem as high morbidity
from the virus leaves populations with negative physical, social, and economic impacts …

mRNA vaccine designing using chikungunya virus E glycoprotein through immunoinformatics-guided approaches

S Jaan, A Zaman, S Ahmed, M Shah, SC Ojha - Vaccines, 2022 - mdpi.com
Chikungunya virus is an alphavirus transmitted by mosquitos that develops into
chikungunya fever and joint pain in humans. This virus' name originated from a Makonde …

Dynamic of Mayaro Virus Transmission in Aedes aegypti, Culex quinquefasciatus Mosquitoes, and a Mice Model

L Krokovsky, CRB Lins, DRD Guedes, GL Wallau… - Viruses, 2023 - mdpi.com
Mayaro virus (MAYV) is transmitted by Haemagogus spp. mosquitoes and has been
circulating in Amazon areas in the North and Central West regions of Brazil since the 1980s …

Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

MS Hakim, AT Aman - Viruses, 2022 - mdpi.com
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by
the sudden onset of symptoms, including fever, rash, myalgia, and headache. In some …