Thyroid and COVID-19: a review on pathophysiological, clinical and organizational aspects
G Lisco, A De Tullio, E Jirillo, VA Giagulli… - Journal of …, 2021 - Springer
Background Thyroid dysfunction has been observed in patients with COVID-19, and
endocrinologists are requested to understand this clinical issue. Pandemic-related …
endocrinologists are requested to understand this clinical issue. Pandemic-related …
[HTML][HTML] A systematic review and meta-analysis: the effect of active cancer treatment on severity of COVID-19
E Yekedüz, G Utkan, Y Ürün - European Journal of Cancer, 2020 - Elsevier
Background The COVID-19 pandemic hit all over the world, and cancer patients are more
vulnerable for COVID-19. The mortality rate may increase up to 25% in solid malignancies …
vulnerable for COVID-19. The mortality rate may increase up to 25% in solid malignancies …
Connecting omics signatures and revealing biological mechanisms with iLINCS
There are only a few platforms that integrate multiple omics data types, bioinformatics tools,
and interfaces for integrative analyses and visualization that do not require programming …
and interfaces for integrative analyses and visualization that do not require programming …
Translational precision medicine: an industry perspective
In the era of precision medicine, digital technologies and artificial intelligence, drug
discovery and development face unprecedented opportunities for product and business …
discovery and development face unprecedented opportunities for product and business …
[HTML][HTML] Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
SARS-CoV-2 has currently precipitated the COVID-19 global health crisis. We developed a
medium-throughput drug-screening system and identified a small-molecule library of 34 of …
medium-throughput drug-screening system and identified a small-molecule library of 34 of …
The roles of signaling pathways in SARS-CoV-2 infection; lessons learned from SARS-CoV and MERS-CoV
N Hemmat, Z Asadzadeh, NK Ahangar… - Archives of …, 2021 - Springer
The number of descriptions of emerging viruses has grown at an unprecedented rate since
the beginning of the 21 st century. Severe acute respiratory syndrome coronavirus 2 (SARS …
the beginning of the 21 st century. Severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] A comprehensive review on the global efforts on vaccines and repurposed drugs for combating COVID-19
The recently discovered coronavirus, known as SARS-CoV-2, is a highly contagious and
potentially lethal viral infection that was declared a pandemic by the World Health …
potentially lethal viral infection that was declared a pandemic by the World Health …
Kinases as potential therapeutic targets for anti-coronaviral therapy
T Pillaiyar, S Laufer - Journal of Medicinal Chemistry, 2021 - ACS Publications
The global coronavirus disease-19 (COVID-19) has affected more than 140 million and
killed more than 3 million people worldwide as of April 20, 2021. The novel human severe …
killed more than 3 million people worldwide as of April 20, 2021. The novel human severe …
A comprehensive review of drug repurposing strategies against known drug targets of COVID-19
Drug repurposing is a more inexpensive and shorter approach than the traditional drug
discovery and development process. The concept of identifying a potent molecule from a …
discovery and development process. The concept of identifying a potent molecule from a …
Estrogen hormone is an essential sex factor inhibiting inflammation and immune response in COVID-19
Although vaccines have been evaluated and approved for SARS-CoV-2 infection
prevention, there remains a lack of effective treatments to reduce the mortality of COVID-19 …
prevention, there remains a lack of effective treatments to reduce the mortality of COVID-19 …