Stroke is the second leading cause of mortality and the major cause of adult physical
disability worldwide. The currently available treatment to recanalize the blood flow in acute …

Traumatic brain injury (TBI) is a major health and socioeconomic problem that affects all
societies. In recent years, patterns of injury have been changing, with more injuries …

The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset,
sporadic Alzheimer's disease (AD). The APOE ε4 allele markedly increases AD risk and …

Aneurysmal subarachnoid hemorrhage (aSAH) is a medical emergency that accounts for
5% of all stroke cases. Individuals affected are typically in the prime of their lives (mean age …

Microdialysis enables the chemistry of the extracellular interstitial space to be monitored.
Use of this technique in patients with acute brain injury has increased our understanding of …

Concussion (or mild traumatic brain injury, mTBI) is a biomechanically induced neurological
injury, resulting in an alteration of mental status, such as confusion or amnesia, which may …

Concussion (mild traumatic brain injury [TBI]), particularly with organized sports, has come to
the forefront of popular culture. Affecting about 1.6 million to 3.8 million athletes a year, its …

This review focuses on the potential for traumatic brain injury to evoke both focal and diffuse
changes within the brain parenchyma, while considering the cellular constituents involved …

Objectives: To analyze the effect of tight glycemic control with the use of intensive insulin
therapy on cerebral glucose metabolism in patients with severe brain injury. Design …

Objective: To determine whether nonconvulsive electrographic post-traumatic seizures
result in increases in intracranial pressure and microdialysis lactate/pyruvate ratio. Design …