Update on the pathomechanism, diagnosis, and treatment options for rheumatoid arthritis
YJ Lin, M Anzaghe, S Schülke - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease that involves multiple joints bilaterally.
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
It is characterized by an inflammation of the tendon (tenosynovitis) resulting in both cartilage …
Macrophage-osteoclast associations: origin, polarization, and subgroups
Y Sun, J Li, X Xie, F Gu, Z Sui, K Zhang… - Frontiers in …, 2021 - frontiersin.org
Cellular associations in the bone microenvironment are involved in modulating the balance
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
between bone remodeling and resorption, which is necessary for maintaining a normal bone …
[PDF][PDF] Regulation of osteoclast differentiation by cytokine networks
DS Amarasekara, H Yun, S Kim, N Lee… - Immune …, 2018 - synapse.koreamed.org
Cytokines play a pivotal role in maintaining bone homeostasis. Osteoclasts (OCs), the sole
bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating …
bone resorbing cells, are regulated by numerous cytokines. Macrophage colony-stimulating …
Chemokine (C–X–C motif) ligand (CXCL) 10 in autoimmune diseases
A Antonelli, SM Ferrari, D Giuggioli, E Ferrannini… - Autoimmunity …, 2014 - Elsevier
Abstract (C–X–C motif) ligand (CXCL) 10 (CXCL10) belongs to the ELR− CXC subfamily
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …
chemokine. CXCL10 exerts its function through binding to chemokine (C–X–C motif) …
Updates on osteoimmunology: what's new on the cross-talk between bone and immune system
M Ponzetti, N Rucci - Frontiers in endocrinology, 2019 - frontiersin.org
The term osteoimmunology was coined many years ago to describe the research field that
deals with the cross-regulation between bone cells and the immune system. As a matter of …
deals with the cross-regulation between bone cells and the immune system. As a matter of …
Chemokines in physiological and pathological bone remodeling
LJ Brylka, T Schinke - Frontiers in immunology, 2019 - frontiersin.org
The bone matrix is constantly remodeled by bone-resorbing osteoclasts and bone-forming
osteoblasts. These two cell types are fundamentally different in terms of progenitor cells …
osteoblasts. These two cell types are fundamentally different in terms of progenitor cells …
Osteoimmunology and the effects of the immune system on bone
H Takayanagi - Nature Reviews Rheumatology, 2009 - nature.com
In the pathogenesis of bone destruction associated with rheumatoid arthritis, the synovium is
a site of active interplay between immune and bone cells. The interaction between T cells …
a site of active interplay between immune and bone cells. The interaction between T cells …
The effect of cytokines on osteoblasts and osteoclasts in bone remodeling in osteoporosis: A review
J Xu, L Yu, F Liu, L Wan, Z Deng - Frontiers in Immunology, 2023 - frontiersin.org
The complicated connections and cross talk between the skeletal system and the immune
system are attracting more attention, which is developing into the field of Osteoimmunology …
system are attracting more attention, which is developing into the field of Osteoimmunology …
CXCR3, inflammation, and autoimmune diseases
S Lacotte, S Brun, S Muller… - Annals of the New York …, 2009 - Wiley Online Library
CXCR3 is a G protein–coupled, seven‐transmembrane receptor that binds and is activated
by the three IFN‐γ‐inducible chemokines of the CXC family named CXCL9, CXCL10, and …
by the three IFN‐γ‐inducible chemokines of the CXC family named CXCL9, CXCL10, and …
CXCL10 and autoimmune diseases
EY Lee, ZH Lee, YW Song - Autoimmunity reviews, 2009 - Elsevier
CXCL10 is a 10 kDa protein, which is categorized functionally as a Th1-chemokine. It binds
to the receptor CXCR3 and regulates immune responses through the activation and …
to the receptor CXCR3 and regulates immune responses through the activation and …