lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications

PC Africa, I Fumagalli, M Bucelli, A Zingaro… - Computer Physics …, 2024 - Elsevier
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

[HTML][HTML] An electromechanics-driven fluid dynamics model for the simulation of the whole human heart

A Zingaro, M Bucelli, R Piersanti, F Regazzoni… - Journal of …, 2024 - Elsevier
We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

[HTML][HTML] lifex-ep: a robust and efficient software for cardiac electrophysiology simulations

PC Africa, R Piersanti, F Regazzoni, M Bucelli… - BMC …, 2023 - Springer
Background Simulating the cardiac function requires the numerical solution of multi-physics
and multi-scale mathematical models. This underscores the need for streamlined, accurate …

[HTML][HTML] The role of computational methods in cardiovascular medicine: a narrative review

I Fumagalli, S Pagani, C Vergara, DA Adebo… - Translational …, 2024 - ncbi.nlm.nih.gov
Methods We developed computational models of the physical processes encompassed by
the heart function (electrophysiology, electrical activation, force generation, mechanics …

[HTML][HTML] Simulating impaired left ventricular–arterial coupling in aging and disease: a systematic review

CCA Ding, S Dokos, AA Bakir, NJ Zamberi… - BioMedical Engineering …, 2024 - Springer
Aortic stenosis, hypertension, and left ventricular hypertrophy often coexist in the elderly,
causing a detrimental mismatch in coupling between the heart and vasculature known as …

[HTML][HTML] A stable loosely-coupled scheme for cardiac electro-fluid-structure interaction

M Bucelli, MG Gabriel, A Quarteroni, G Gigante… - Journal of …, 2023 - Elsevier
We present a loosely coupled scheme for the numerical simulation of the cardiac electro-
fluid-structure interaction problem, whose solution is typically computationally intensive due …

Modeling isovolumetric phases in cardiac flows by an augmented resistive immersed implicit surface method

A Zingaro, M Bucelli, I Fumagalli… - International Journal …, 2023 - Wiley Online Library
A major challenge in the computational fluid dynamics modeling of the heart function is the
simulation of isovolumetric phases when the hemodynamics problem is driven by a …

A staggered-in-time and non-conforming-in-space numerical framework for realistic cardiac electrophysiology outputs

E Zappon, A Manzoni, A Quarteroni - arXiv preprint arXiv:2308.03884, 2023 - arxiv.org
Computer-based simulations of non-invasive cardiac electrical outputs, such as
electrocardiograms and body surface potential maps, usually entail severe computational …

An integrated heart–torso electromechanical model for the simulation of electrophysiological outputs accounting for myocardial deformation

E Zappon, M Salvador, R Piersanti, F Regazzoni… - Computer Methods in …, 2024 - Elsevier
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms
(ECGs) and body surface potential maps (BSPMs), mathematical models have relied on …

FSGe: A fast and strongly-coupled 3D fluid-solid-growth interaction method

MR Pfaller, M Latorre, EL Schwarz, FM Gerosa… - arXiv preprint arXiv …, 2024 - arxiv.org
Equilibrated fluid-solid-growth (FSGe) is a fast, open source, three-dimensional (3D)
computational platform for simulating interactions between instantaneous hemodynamics …