BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

Background: Preimplantation genetic testing (PGT) is widely used today in in-vitro
fertilization (IVF) centers over the world for selecting euploid embryos for transfer and to …

Purpose This study aimed to analyze the impact of different biopsy protocols on the rate of
mosaic blastocysts. Methods This is a retrospective cohort study which included 115 cycles …

The sperm is essential for reconstitution of embryonic diploidy and highly specialized
developmental functions. Immediately after gamete fusion, the sperm-borne PLC-zeta …

Background Preimplantation genetic testing for aneuploidy (PGT-A) is widely used as an
embryo selection technique in in vitro fertilization (IVF), but its effectiveness and potential …

Research question Are intrinsic or extrinsic factors associated with embryo mosaicism
prevalence in IVF cycles? Design Retrospective cohort study of preimplantation genetic …

Male infertility contributes as the main factor in 30–50% of infertility cases. Conventional
methods for sperm preparation have induced questioning of sperm recovery rates. The …

Purpose Evaluate which factors are involved in the increased rate of mosaicism in embryos.
Methods A systematic review and meta-analysis was performed. After an exhaustive search …

Background Early rescue intracytoplasmic sperm injection (ICSI) has been used in clinic as
appropriate currently. While the outcomes of children born after this method were not well …

Highly sensitive next-generation sequencing (NGS) platforms applied to preimplantation
genetic testing for aneuploidy (PGT-A) allow the classification of mosaicism in …