[HTML][HTML] Critical protein GAPDH and its regulatory mechanisms in cancer cells

JY Zhang, F Zhang, CQ Hong, AE Giuliano… - Cancer biology & …, 2015 - ncbi.nlm.nih.gov
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), initially identified as a
glycolytic enzyme and considered as a housekeeping gene, is widely used as an internal …

Evolution of the apicoplast and its hosts: from heterotrophy to autotrophy and back again

M Oborník, J Janouškovec, T Chrudimský… - International journal for …, 2009 - Elsevier
The photosynthetic origin of apicomplexan parasites was proposed upon the discovery of a
reduced non-photosynthetic plastid termed the apicoplast in their cells. Although it is clear …

Excretory/secretory proteome of the adult developmental stage of human blood fluke, Schistosoma japonicum

F Liu, SJ Cui, W Hu, Z Feng, ZQ Wang… - Molecular & Cellular …, 2009 - ASBMB
Schistosomes are the causative agents of schistosomiasis, one of the most prevalent and
serious of the parasitic diseases that currently infects∼ 200 million people worldwide …

Glyceradehyde-3-phosphate dehydrogenase as a suitable vaccine candidate for protection against bacterial and parasitic diseases

J Perez-Casal, AA Potter - Vaccine, 2016 - Elsevier
Abstract The enzyme glyceraldehyde-3-P-dehydrogenase (GAPDH) has been identified as
having other properties in addition to its key role in glycolysis. The ability of GAPDH to bind …

Control and regulation of the pyrophosphate-dependent glucose metabolism in Entamoeba histolytica

E Saavedra, R Encalada, C Vázquez… - Molecular and …, 2019 - Elsevier
Entamoeba histolytica has neither Krebs cycle nor oxidative phosphorylation activities;
therefore, glycolysis is the main pathway for ATP supply and provision of carbon skeleton …

Analyzing the interaction of Helicobacter pylori GAPDH with host molecules and hemin: Inhibition of hemin binding

T Priyadharshini, P Ragunathan, K Ponnuraj - Biophysical Chemistry, 2024 - Elsevier
Abstract Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is a moonlighting enzyme.
Apart from its primary role in the glycolytic pathway, in many bacterial species it is found in …

N-acetyl ornithine deacetylase is a moonlighting protein and is involved in the adaptation of Entamoeba histolytica to nitrosative stress

P Shahi, M Trebicz-Geffen, S Nagaraja, R Hertz… - Scientific reports, 2016 - nature.com
Adaptation of the Entamoeba histolytica parasite to toxic levels of nitric oxide (NO) that are
produced by phagocytes may be essential for the establishment of chronic amebiasis and …

NAD+-dependent post-translational modification of Escherichia coli glyceraldehyde-3-phosphate dehydrogenase

ML Aguilera Gil, R Giménez Claudio… - … , vol. 12, núm. 3, p. 187 …, 2009 - diposit.ub.edu
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional housekeeping
protein reported to be a target of several covalent modifications in many organisms. In a …

Comparative genomics and interactomics of polyadenylation factors for the prediction of new parasite targets: Entamoeba histolytica as a working model

RG Avila-Bonilla, JA Velazquez-Guzman… - Bioscience …, 2023 - portlandpress.com
Protein–protein interactions (PPI) play a key role in predicting the function of a target protein
and drug ability to affect an entire biological system. Prediction of PPI networks greatly …

Identification of virulence-associated factors in Vibrio parahaemolyticus with special reference to moonlighting protein: a secretomics study

P Paria, HJ Chakraborty, A Pakhira, MS Devi… - International …, 2024 - Springer
Vibrio parahaemolyticus causes seafood-borne gastroenteritis infection in human which can
even lead to death. The pathogenic strain of V. parahaemolyticus secretes different types of …