Associations between drug treatments and the risk of aneurysmal subarachnoid hemorrhage: A systematic review and meta-analysis

K Shimizu, T Aoki, N Etminan, KAM Hackenberg… - Translational Stroke …, 2023 - Springer
There is increasing interest in drug therapy for preventing aneurysmal subarachnoid
hemorrhage (aSAH). We aimed to comprehensively evaluate the association between drug …

Animal Models of Intracranial Aneurysms: History, Advances, and Future Perspectives

H Uchikawa, R Rahmani - Translational Stroke Research, 2024 - Springer
Intracranial aneurysms (IA) are a disease process with potentially devastating outcomes,
particularly when rupture occurs leading to subarachnoid hemorrhage. While some …

Effect of renin-angiotensin-aldosterone system inhibitors on the rupture risk among hypertensive patients with intracranial aneurysms

P Zhong, Z Lu, Z Li, T Li, Q Lan, J Liu, Z Wang… - …, 2022 - Am Heart Assoc
Background: Mounting experimental evidence supports the concept that the RAAS (renin-
angiotensin-aldosterone system) is involved in the pathogenesis of intracranial aneurysm …

[HTML][HTML] Identifying and validating key genes mediating intracranial aneurysm rupture using weighted correlation network analysis and exploration of personalized …

J Wu, ZJ Chen, J Liang, CS Lai, XY Li… - Annals of translational …, 2022 - ncbi.nlm.nih.gov
Background Intracranial aneurysmal subarachnoid hemorrhage (aSAH) is a dangerous and
highly fatal condition if ruptured. Significant advances have been made in the treatment of …

Hypoxic microenvironment as a crucial factor triggering events leading to rupture of intracranial aneurysm

I Ono, T Kayahara, A Kawashima, A Okada… - Scientific reports, 2023 - nature.com
Subarachnoid hemorrhage being the rupture of intracranial aneurysm (IA) as a major cause
has quite poor prognosis, despite the modern technical advances. Thereby, the mechanisms …

Pharmaceutical Modulation of Intracranial Aneurysm Development and Rupture

A Crane, RM Shanahan, JS Hudson… - Journal of Clinical …, 2024 - mdpi.com
Management of intracranial aneurysms (IAs) is determined by patient age, risk of rupture,
and comorbid conditions. While endovascular and microsurgical interventions offer solutions …

Genetically determined blood pressure, antihypertensive medications, and risk of intracranial aneurysms and aneurysmal subarachnoid hemorrhage: A Mendelian …

H Liu, H Zuo, O Johanna, R Zhao… - European Stroke …, 2024 - journals.sagepub.com
Introduction: Observational studies suggest that different classes of antihypertensive drugs
may have different effects on the occurrence of intracranial aneurysms (IA) and …

Prescribed Drug Use and Aneurysmal Subarachnoid Hemorrhage Incidence: A Drug-Wide Association Study

JP Kanning, S Abtahi, C Schnier, OH Klungel… - Neurology, 2024 - AAN Enterprises
Background and Objectives Current benefits of invasive intracranial aneurysm treatment to
prevent aneurysmal subarachnoid hemorrhage (aSAH) rarely outweigh treatment risks. Most …

Medications and “Risk” of Aneurysm Rupture Based on Presentation: Setting the Record Straight

SS Hoz, JS Hudson, L Ma, MJ Lang, BA Gross - World Neurosurgery, 2024 - Elsevier
Objectives Studies assessing aneurysm rupture “risk” based on comparative retrospective
analyses of medications taken on presentation may be subject to presentation bias. Are …

[HTML][HTML] Hemodynamics in Intracranial Aneurysm Formation

H Koseki - 2024 - intechopen.com
Intracranial aneurysms (IAs) are dilated lesions of the arterial wall caused by a dysfunction
of the hemodynamic stress, leading to subarachnoid hemorrhage, which can be devastating …