Publisher Summary This chapter reviews the histopathologic, serologic, lymphocytic,
virological, hormonal, and genetic characteristics of murine models of systemic lupus …

Dendritic cells (DC) present Ag to naive T cells and are therefore pivotal in shaping immune
responses. DC may either immunize or tolerize T cells. Humans with pancreatic islet …

The autologous mixed lymphocyte reaction (AMLR) represents the activation, proliferation
and differentiation of T cells in response to signals from autologous non‐T cells. Upon …

A limiting dilution system has been applied to compare precursor frequencies of proliferating
T lymphocytes (PTL-P), of T-cell growth factor-secreting T cells (TTCGF-P), and of cytotoxic T …

Patients with schistosomiasis of the urinary bladder (SB) associated with carcinoma of the
bladder (SCB) or carcinoma of the prostate (SCP) have a variety of immunologic …

Since the modulation of the immune system at birth may influence the course of insulin‐
dependent (type 1) diabetes, we investigated whether neonatal injections of cyclosporin …

Autoimmune mice bearing the single autosomal recessive gene 1pr are unable to produce
the T cell growth factor, interleukin-2 (IL-2). A physiological consequence of this defect is the …

Monoclonal antibodies with specificity for autoreactive murine T cells have been developed.
These antibodies inhibit proliferative response of splenic T cells activated by syngeneic …

The autologous mixed lymphocyte reaction (AMLR) can be detected in older NZB mice after
treatment of the responding cell population with monoclonal anti-IA d and complement and …

Recent studies have suggested the existence of two mutually exclusive subpopulations of T
helper (Th) cells in the murine immune system, called Th1 which produces interleukin (IL)-2 …