Amorphous solid dispersions: Stability mechanism, design strategy and key production technique of hot melt extrusion
J Han, M Tang, Y Yang, W Sun, Z Yue, Y Zhang… - International Journal of …, 2023 - Elsevier
Solid dispersion (SD) system has been used as an effective formulation strategy to increase
in vitro and in vivo performances of poorly water-soluble drugs, such as …
in vitro and in vivo performances of poorly water-soluble drugs, such as …
Can Pure Predictions of Activity Coefficients from PC-SAFT Assist Drug–Polymer Compatibility Screening?
J Pavliš, A Mathers, M Fulem… - Molecular …, 2023 - ACS Publications
The bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) can be
improved via the formulation of an amorphous solid dispersion (ASD), where the API is …
improved via the formulation of an amorphous solid dispersion (ASD), where the API is …
Glass Transition and Structure of Organic Polymers from All-Atom Molecular Simulations
M Klajmon, V Aulich, J Ludík… - Industrial & Engineering …, 2023 - ACS Publications
Molecular dynamics simulations of polymer samples with all-atom resolution provide
important insight into the relationship between the atom-level structure and macroscopic …
important insight into the relationship between the atom-level structure and macroscopic …
Towards rational design of API-poly (D, L-lactide-co-glycolide) based micro-and nanoparticles: The role of API-polymer compatibility prediction
A Iemtsev, ALV Zumaya, M Dinh, F Hassouna… - International Journal of …, 2024 - Elsevier
Due to their unique properties, such as controlled drug release and improved bioavailability,
polymeric microparticles and nanoparticles (MPs and NPs) have gained considerable …
polymeric microparticles and nanoparticles (MPs and NPs) have gained considerable …