[HTML][HTML] Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …
The exosomes in tumor immunity
Y Liu, Y Gu, X Cao - Oncoimmunology, 2015 - Taylor & Francis
Exosomes are a kind of nanometric membrane vesicles and can be released by almost all
kinds of cells, including cancer cells. As the important mediators in intercellular …
kinds of cells, including cancer cells. As the important mediators in intercellular …
[HTML][HTML] Magnetic enrichment of dendritic cell vaccine in lymph node with fluorescent-magnetic nanoparticles enhanced cancer immunotherapy
Dendritic cell (DC) migration to the lymph node is a key component of DC-based
immunotherapy. However, the DC homing rate to the lymphoid tissues is poor, thus …
immunotherapy. However, the DC homing rate to the lymphoid tissues is poor, thus …
Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer
Z Zhou, H Chen, R Xie, H Wang, S Li, Q Xu… - Molecular …, 2019 - Wiley Online Library
Forkhead box transcription factor M1 (FOXM 1) is a proliferation‐associated transcription
factor involved in tumorigenesis through transcriptional regulation of its target genes in …
factor involved in tumorigenesis through transcriptional regulation of its target genes in …
Nanoparticle-based approaches to target the lymphatic system for antitumor treatment
Immunotherapies have been established as safe and efficient modalities for numerous
tumor treatments. The lymphatic system, which is an important system, can modulate the …
tumor treatments. The lymphatic system, which is an important system, can modulate the …
Gelsolin inhibits the inflammatory process induced by LPS
Y Cheng, X Hu, C Liu, M Chen, J Wang… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Endotoxemia is a life-threatening situation that signifies a key
challenge in the field of intensive care medicine. Proinflammatory mediators produced by …
challenge in the field of intensive care medicine. Proinflammatory mediators produced by …
microRNA-155 deficiency impairs dendritic cell function in breast cancer
J Wang, S Iwanowycz, F Yu, X Jia, S Leng… - …, 2016 - Taylor & Francis
In antitumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …
β-Glucan enhances cytotoxic T lymphocyte responses by activation of human monocyte-derived dendritic cells via the PI3K/AKT pathway
J Ding, T Feng, Y Ning, W Li, Q Wu, K Qian, Y Wang… - Human Immunology, 2015 - Elsevier
Purpose To investigate the effects of β-(1, 3/1, 6)-d-glucan on dendritic cells (DCs)
maturation, cytotoxic T lymphocyte responses and the molecular mechanisms of its …
maturation, cytotoxic T lymphocyte responses and the molecular mechanisms of its …
Intratumoral dendritic cells in the anti-tumor immune response
Y Liu, X Cao - Cellular & molecular immunology, 2015 - nature.com
Immunotherapy has become a po-pular approach to the treatment of cancer and is well
known in the clinical management of cancer because of the exciting recent results from …
known in the clinical management of cancer because of the exciting recent results from …
Design and immunological evaluation of anti-CD205-tailored PLGA-based nanoparticulate cancer vaccine
The aim of this research was to develop a targeted antigen–adjuvant assembled delivery
system that will enable dendritic cells (DCs) to efficiently mature to recognize antigens …
system that will enable dendritic cells (DCs) to efficiently mature to recognize antigens …