[HTML][HTML] Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy

J Jia, Y Zhang, Y Xin, C Jiang, B Yan, S Zhai - Frontiers in oncology, 2018 - frontiersin.org
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …

The exosomes in tumor immunity

Y Liu, Y Gu, X Cao - Oncoimmunology, 2015 - Taylor & Francis
Exosomes are a kind of nanometric membrane vesicles and can be released by almost all
kinds of cells, including cancer cells. As the important mediators in intercellular …

[HTML][HTML] Magnetic enrichment of dendritic cell vaccine in lymph node with fluorescent-magnetic nanoparticles enhanced cancer immunotherapy

H Jin, Y Qian, Y Dai, S Qiao, C Huang, L Lu, Q Luo… - Theranostics, 2016 - ncbi.nlm.nih.gov
Dendritic cell (DC) migration to the lymph node is a key component of DC-based
immunotherapy. However, the DC homing rate to the lymphoid tissues is poor, thus …

Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer

Z Zhou, H Chen, R Xie, H Wang, S Li, Q Xu… - Molecular …, 2019 - Wiley Online Library
Forkhead box transcription factor M1 (FOXM 1) is a proliferation‐associated transcription
factor involved in tumorigenesis through transcriptional regulation of its target genes in …

Nanoparticle-based approaches to target the lymphatic system for antitumor treatment

X Peng, J Wang, F Zhou, Q Liu, Z Zhang - Cellular and Molecular Life …, 2021 - Springer
Immunotherapies have been established as safe and efficient modalities for numerous
tumor treatments. The lymphatic system, which is an important system, can modulate the …

Gelsolin inhibits the inflammatory process induced by LPS

Y Cheng, X Hu, C Liu, M Chen, J Wang… - Cellular Physiology and …, 2017 - karger.com
Abstract Background/Aims: Endotoxemia is a life-threatening situation that signifies a key
challenge in the field of intensive care medicine. Proinflammatory mediators produced by …

microRNA-155 deficiency impairs dendritic cell function in breast cancer

J Wang, S Iwanowycz, F Yu, X Jia, S Leng… - …, 2016 - Taylor & Francis
In antitumor immunity, dendritic cells (DCs) capture, process, and present tumor antigens to
T cells, initiating a tumoricidal response. However, DCs are often dysfunctional due to their …

β-Glucan enhances cytotoxic T lymphocyte responses by activation of human monocyte-derived dendritic cells via the PI3K/AKT pathway

J Ding, T Feng, Y Ning, W Li, Q Wu, K Qian, Y Wang… - Human Immunology, 2015 - Elsevier
Purpose To investigate the effects of β-(1, 3/1, 6)-d-glucan on dendritic cells (DCs)
maturation, cytotoxic T lymphocyte responses and the molecular mechanisms of its …

Intratumoral dendritic cells in the anti-tumor immune response

Y Liu, X Cao - Cellular & molecular immunology, 2015 - nature.com
Immunotherapy has become a po-pular approach to the treatment of cancer and is well
known in the clinical management of cancer because of the exciting recent results from …

Design and immunological evaluation of anti-CD205-tailored PLGA-based nanoparticulate cancer vaccine

ST Jahan, SMA Sadat, A Haddadi - International journal of …, 2018 - Taylor & Francis
The aim of this research was to develop a targeted antigen–adjuvant assembled delivery
system that will enable dendritic cells (DCs) to efficiently mature to recognize antigens …