[HTML][HTML] Improving curcumin bioavailability: Current strategies and future perspectives
R Tabanelli, S Brogi, V Calderone - Pharmaceutics, 2021 - mdpi.com
Curcumin possesses a plethora of interesting pharmacological effects. Unfortunately, it is
also characterized by problematic drug delivery and scarce bioavailability, representing the …
also characterized by problematic drug delivery and scarce bioavailability, representing the …
[HTML][HTML] The chemistry of curcumin: from extraction to therapeutic agent
KI Priyadarsini - Molecules, 2014 - mdpi.com
Curcumin, a pigment from turmeric, is one of the very few promising natural products that
has been extensively investigated by researchers from both the biological and chemical …
has been extensively investigated by researchers from both the biological and chemical …
[HTML][HTML] Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis
D Thomas, P Radhakrishnan - Molecular cancer, 2019 - Springer
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with high morbidity and
mortality worldwide. To date, limited therapeutic achievements targeting cell proliferation …
mortality worldwide. To date, limited therapeutic achievements targeting cell proliferation …
[HTML][HTML] Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug …
Introduction Tumor cells can effectively be killed by heat, eg by using magnetic
hyperthermia. The main challenge in the field, however, is the generation of therapeutic …
hyperthermia. The main challenge in the field, however, is the generation of therapeutic …
[HTML][HTML] PGMD/curcumin nanoparticles for the treatment of breast cancer
The present study aims at developing PGMD (poly-glycerol-malic acid-dodecanedioic
acid)/curcumin nanoparticles based formulation for anticancer activity against breast cancer …
acid)/curcumin nanoparticles based formulation for anticancer activity against breast cancer …
Curcumin as potential therapeutic natural product: a nanobiotechnological perspective
S Shome, AD Talukdar, MD Choudhury… - Journal of Pharmacy …, 2016 - academic.oup.com
Objectives Nanotechnology-based drug delivery systems can resolve the poor
bioavailability issue allied with curcumin. The therapeutic potential of curcumin can be …
bioavailability issue allied with curcumin. The therapeutic potential of curcumin can be …
Curcumin as a clinically-promising anti-cancer agent: pharmacokinetics and drug interactions
J Adiwidjaja, AJ McLachlan… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: Curcumin has been extensively studied for its anti-cancer properties. While a
diverse array of in vitro and preclinical research support the prospect of curcumin use as an …
diverse array of in vitro and preclinical research support the prospect of curcumin use as an …
Superparamagnetic iron oxide nanoparticles of curcumin enhance gemcitabine therapeutic response in pancreatic cancer
Pancreatic cancer is a complex disease accounting for fibrotic tumors and an aggressive
phenotype. Gemcitabine (GEM) is used as a standard therapy, which develops …
phenotype. Gemcitabine (GEM) is used as a standard therapy, which develops …
[HTML][HTML] Antitumoral activities of curcumin and recent advances to improve its oral bioavailability
MC Nocito, A De Luca, F Prestia, P Avena, D La Padula… - Biomedicines, 2021 - mdpi.com
Curcumin, a main bioactive component of the Curcuma longa L. rhizome, is a phenolic
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …
compound that exerts a wide range of beneficial effects, acting as an antimicrobial …
Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy
JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …
They show antitumor properties. However, a key problem is their short half-life and low …