There is a genetic component to human obesity that accounts for 40% to 50% of the
variability in body weight status but that is lower among normal weight individuals (about …

The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …

Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …

Thermogenesis in brown and beige adipose tissue has important roles in maintaining body
temperature and countering the development of metabolic disorders such as obesity and …

Growing evidence suggests that relative carbohydrate intake affects depression; however,
the association between carbohydrates and depression remains controversial. To test this …

Biobanks often contain several phenotypes relevant to diseases such as major depressive
disorder (MDD), with partly distinct genetic architectures. Researchers face complex …

The Pacific region is of major importance for addressing questions regarding human
dispersals, interactions with archaic hominins and natural selection processes. However, the …

There is currently limited understanding of the genetic aetiology of obstructive sleep apnoea
(OSA). We aimed to identify genetic loci associated with OSA risk, and to test if OSA and its …

Background Observational studies have investigated the association of risk factors with
breast cancer prognosis. However, the results have been conflicting and it has been …

Background Natural and artificial directional selection in cosmopolitan and autochthonous
pig breeds and wild boars have shaped their genomes and resulted in a reservoir of animal …