Olfactory receptor (OR) choice provides an extreme example of allelic competition for
transcriptional dominance, where every olfactory neuron stably transcribes one of …

Life inside ant colonies is orchestrated with diverse pheromones, but it is not clear how ants
perceive these social signals. It has been proposed that pheromone perception in ants …

The molecular mechanisms underlying the axon arborization of mammalian neurons are
poorly understood but are critical for the establishment of functional neural circuits. We …

The quest to determine how precise neural activity patterns mediate computation, behavior,
and pathology would be greatly aided by a set of tools for reliably activating and inactivating …

Patterns of synaptic connections in the visual system are remarkably precise. These
connections dictate the receptive field properties of individual visual neurons and ultimately …

The brain receives sensory input from diverse peripheral tissues, including the skin, the
body's largest sensory organ. Using genetically encoded axonal tracers expressed from the …

Odor signals received by odorant receptors (ORs) expressed by olfactory sensory neurons
(OSNs) in the olfactory epithelium (OE) are represented as an odor map in the olfactory bulb …

A significant challenge for neuroscientists is to determine how both electrical and chemical
signals affect the activity of cells and circuits and how the nervous system subsequently …

Gene positioning and regulation of nuclear architecture are thought to influence gene
expression. Here, we show that, in mouse olfactory neurons, silent olfactory receptor (OR) …

Ca2+ triggers many forms of exocytosis in different types of eukaryotic cells, for example
synaptic vesicle exocytosis in neurons, granule exocytosis in mast cells, and hormone …