Accurate sensory processing during movement requires the animal to distinguish between
external (exafferent) and self-generated (reafferent) stimuli to maintain sensitivity to …

The Ca2+-activated Cl− channel TMEM16B is highly expressed in the cilia of olfactory
sensory neurons (OSNs). Although a large portion of the odor-evoked transduction current is …

Cyclic nucleotide phosphodiesterase 10A (PDE10A) is a member of phosphodiesterase
families that degrade cAMP and/or cGMP in distinct intracellular sites. PDE10A has a dual …

Olfaction is essential for complex social behavior in insects. To discriminate complex social
cues, ants evolved an expanded number of odorant receptor (Or) genes. Mutations in the …

Post-infectious anosmias typically follow death of olfactory sensory neurons (OSNs) with a
months-long recovery phase associated with parosmias. While profound anosmia is the …

Incorporation of new neurons enables plasticity and repair of circuits in the adult brain. Adult
neurogenesis is a key feature of the mammalian olfactory system, with new olfactory sensory …

Activity-dependent synaptic remodeling occurs during early-use critical periods, when naive
juveniles experience sensory input. Fragile X mental retardation protein (FMRP) sculpts …

Within the central nervous system, the olfactory system fascinates by its developmental and
physiological particularities, and is one of the most studied models to understand the …

Ion channels are the determinants of excitability; therefore, manipulation of their levels and
properties provides an opportunity for the investigator to modulate neuronal and circuit …

Neuronal wiring plasticity in response to experience or injury has been reported in many
parts of the adult nervous system. For instance, visual or somatosensory cortical maps can …