Mice with a “monoclonal nose”: perturbations in an olfactory map impair odor discrimination

A Fleischmann, BM Shykind, DL Sosulski, KM Franks… - Neuron, 2008 - cell.com
We have altered the neural representation of odors in the brain by generating a mouse with
a" monoclonal nose" in which greater than 95% of the sensory neurons express a single …

The neuroregenerative capacity of olfactory stem cells is not limitless: implications for aging

KM Child, DB Herrick, JE Schwob… - Journal of …, 2018 - Soc Neuroscience
The olfactory epithelium (OE) of vertebrates is a highly regenerative neuroepithelium that is
maintained under normal conditions by a population of stem and progenitor cells, globose …

Multiple forms of activity-dependent competition refine hippocampal circuits in vivo

M Yasuda, EM Johnson-Venkatesh, H Zhang… - Neuron, 2011 - cell.com
Efficient memory formation relies on the establishment of functional hippocampal circuits. It
has been proposed that synaptic connections are refined by neural activity to form functional …

Purinergic signaling in cochlear supporting cells reduces hair cell excitability by increasing the extracellular space

TA Babola, CJ Kersbergen, HC Wang, DE Bergles - Elife, 2020 - elifesciences.org
Neurons in developing sensory pathways exhibit spontaneous bursts of electrical activity
that are critical for survival, maturation and circuit refinement. In the auditory system …

Modulation of spontaneous and odorant-evoked activity of rat olfactory sensory neurons by two anorectic peptides, insulin and leptin

A Savigner, P Duchamp-Viret… - Journal of …, 2009 - journals.physiology.org
In mammals, the sense of smell is modulated by the status of satiety, which is mainly
signaled by blood-circulating peptide hormones. However, the underlying mechanisms …

Integrated action of pheromone signals in promoting courtship behavior in male mice

S Haga-Yamanaka, L Ma, J He, Q Qiu, LD Lavis… - Elife, 2014 - elifesciences.org
The mammalian vomeronasal organ encodes pheromone information about gender,
reproductive status, genetic background and individual differences. It remains unknown how …

Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map

DF Albeanu, AC Provost, P Agarwal, ER Soucy… - Nature …, 2018 - nature.com
Inputs from olfactory sensory neuron (OSN) axons expressing the same type of odorant
receptor (OR) converge in the glomerulus of the main olfactory bulb. A key marker of mature …

[图书][B] The neurobiology of olfaction

A Menini - 2009 - taylorfrancis.com
Comprehensive Overview of Advances in OlfactionThe common belief is that human smell
perception is much reduced compared with other mammals, so that whatever abilities are …

Topographic mapping—the olfactory system

T Imai, H Sakano, LB Vosshall - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
Sensory systems must map accurate representations of the external world in the brain.
Although the physical senses of touch and vision build topographic representations of the …

The role of the odorant receptors in the formation of the sensory map

S Francia, C Lodovichi - BMC biology, 2021 - Springer
In the olfactory system, odorant receptors (ORs) expressed at the cell membrane of olfactory
sensory neurons detect odorants and direct sensory axons toward precise target locations in …