Background Metagenomic next-generation sequencing (mNGS) has changed the diagnosis
landscape of lower respiratory tract infections (LRIs). With the development of newer …

Background Early detection of pathogen-associated diseases are critical for effective
treatment. Rapid, specific, sensitive, and cost-effective diagnostic technologies continue to …

Abstract Background Oxford Nanopore Technologies (ONT) offers an accessible platform for
long-read sequencing, which improves the reconstruction of genomes and helps to resolve …

Lower respiratory tract infections (LRTIs) have high morbidity and mortality rates. However,
traditional etiological detection methods have not been able to meet the needs for the …

Fast and accurate identification of microbial pathogens is critical for the proper treatment of
infections. Traditional culture‐based diagnosis in clinics is increasingly supplemented by …

Acute respiratory infection is the third most frequent cause of mortality worldwide, causing
over 4.25 million deaths annually. Although most diagnosed acute respiratory infections are …

Purpose Metagenomic next-generation sequencing (mNGS) is widely used for pulmonary
infection; nonetheless, the experience from its clinical use in diagnosing pulmonary fungal …

In late December 2019, the first cases of viral pneumonia caused by an unidentified
pathogen were reported in China. Two years later, SARS-CoV-2 was responsible for almost …

Pathogen detection from biological and environmental samples is important for global
disease control. Despite advances in pathogen detection using deep learning, current …

Background Infectious disease is a large burden on public health globally. Metagenomic
next-generation sequencing (mNGS) has become popular as a new tool for pathogen …