Lower and upper respiratory infections are the fourth highest cause of global mortality.
Epidemic and pandemic outbreaks of respiratory infection are a major medical concern …

Antimicrobial drugs are key tools to prevent and treat bacterial infections. Despite the early
success of antibiotics, the current treatment of bacterial infections faces serious challenges …

Bacterial meningitis is a severe infectious disease of the membranes lining the brain
resulting in a high mortality and morbidity throughout the world. In the past decades the …

Rapid diagnosis and treatment of infectious meningitis and encephalitis are critical to
minimize morbidity and mortality. Comprehensive testing of cerebrospinal fluid (CSF) often …

Bacterial meningitis is a global public health concern, with several responsible etiologic
agents that vary by age group and geographical area. The aim of this systematic review and …

Background We studied causative pathogens, clinical characteristics, and outcome of adult
community-acquired bacterial meningitis after the introduction of adjunctive dexamethasone …

The blood–brain barrier (BBB) maintains the optimal microenvironment in the central
nervous system (CNS) for proper brain function. The BBB comprises specialized CNS …

Meningitis is an inflammation of the meninges and subarachnoid space that can also involve
the brain cortex and parenchyma. It can be acquired spontaneously in the community …

Summary Background The FilmArray Meningitis/Encephalitis (FA/ME) panel brings benefits
in clinical practice, but its diagnostic test accuracy (DTA) remains unclear. We aimed to …

Pneumococcal meningitis continues to be associated with high rates of mortality and long-
term neurological sequelae. The most common route of infection starts by nasopharyngeal …