[HTML][HTML] Implications of AlphaFold2 for crystallographic phasing by molecular replacement
The AlphaFold2 results in the 14th edition of Critical Assessment of Structure Prediction
(CASP14) showed that accurate (low root-mean-square deviation) in silico models of protein …
(CASP14) showed that accurate (low root-mean-square deviation) in silico models of protein …
Structural insights into type III secretion systems of the bacterial flagellum and injectisome
LJ Worrall, DD Majewski… - Annual Review of …, 2023 - annualreviews.org
Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …
Direct interaction of a chaperone-bound type III secretion substrate with the export gate
D Gilzer, M Schreiner, HH Niemann - Nature Communications, 2022 - nature.com
Several gram-negative bacteria employ type III secretion systems (T3SS) to inject effector
proteins into eukaryotic host cells directly from the bacterial cytoplasm. The export gate SctV …
proteins into eukaryotic host cells directly from the bacterial cytoplasm. The export gate SctV …
[HTML][HTML] Recent structural advances towards understanding of the bacterial type III secretion injectisome
J Jenkins, LJ Worrall, NCJ Strynadka - Trends in Biochemical Sciences, 2022 - cell.com
The bacterial injectisome is a structurally conserved, syringe-shaped nanomachine that
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …
Virulence-associated type III secretion systems in Gram-negative bacteria
Virulence-associated bacterial type III secretion systems are multiprotein molecular
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …
Chaperone Recycling in Late-Stage Flagellar Assembly
The flagellum is a sophisticated nanomachine responsible for motility in Gram-negative
bacteria. Flagellar assembly is a strictly choreographed process, in which the motor and …
bacteria. Flagellar assembly is a strictly choreographed process, in which the motor and …
Protein export via the type III secretion system of the bacterial flagellum
The bacterial flagellum and the related virulence-associated injectisome system of
pathogenic bacteria utilize a type III secretion system (T3SS) to export substrate proteins …
pathogenic bacteria utilize a type III secretion system (T3SS) to export substrate proteins …
Nonameric structures of the cytoplasmic domain of FlhA and SctV in the context of the full-length protein
Type three secretion is the mechanism of protein secretion found in bacterial flagella and
injectisomes. At its centre is the export apparatus (EA), a complex of five membrane proteins …
injectisomes. At its centre is the export apparatus (EA), a complex of five membrane proteins …
Membrane voltage-dependent activation mechanism of the bacterial flagellar protein export apparatus
T Minamino, YV Morimoto… - Proceedings of the …, 2021 - National Acad Sciences
The proton motive force (PMF) consists of the electric potential difference (Δψ), which is
measured as membrane voltage, and the proton concentration difference (ΔpH) across the …
measured as membrane voltage, and the proton concentration difference (ΔpH) across the …
The FlgN chaperone activates the Na+-driven engine of the Salmonella flagellar protein export apparatus
The bacterial flagellar protein export machinery consists of a transmembrane export gate
complex and a cytoplasmic ATPase complex. The gate complex has two intrinsic and distinct …
complex and a cytoplasmic ATPase complex. The gate complex has two intrinsic and distinct …