Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

Cancer stem cells (CSCs) have emerged as key contributors to tumor initiation, growth, and
metastasis. In addition, CSCs play a significant role in inducing immune evasion, thereby …

Gastric cancer (GC) was the fourth deadliest cancer in the world in 2020, and about 770,000
people died from GC that year. The death of patients with GC is mainly caused by the …

Unlike other normal cells, a subpopulation of cells often termed as “stem cells” are long-lived
and generate cellular progeny throughout life. Cancer stem cells (CSCs) are rare immortal …

The progression of most human cancers mainly involves the gradual accumulation of the
loss of differentiated phenotypes and the sequential acquisition of progenitor and stem cell …

Cancer is recognized as a preeminent factor of the world's mortality. Although various
modalities have been designed to cure this life-threatening ailment, a significant impediment …

Simple Summary The Notch signaling pathway regulates cell proliferation, apoptosis, stem
cell self-renewal, and differentiation in a context-dependent fashion both during embryonic …

Cancer is characterized by an abnormal growth of the cells in an uncontrolled manner.
These cells have the potential to invade and can eventually turn into malignancy, leading to …

Background Optimising breast cancer treatment remains a challenge. Resistance to therapy
is a major problem in both ER-and ER+ breast cancer. Tumour recurrence after …

Background: Blocking and even reversing gastric precancerous lesions (GPL) is a key
measure to lower the incidence of gastric cancer. Atractylenolide III (AT-III) is a mainly active …