Over the past 15 years, investigators have shown that T lymphocytes can recognize not only
peptides in the context of MHC class I and class II molecules but also foreign and self-lipids …

To optimize vaccination strategies, it is important to use protocols that can'jump-start'immune
responses by harnessing cells of the innate immune system to assist the expansion of …

NKT cells are a relatively newly recognized member of the immune community, with
profound effects on the rest of the immune system despite their small numbers. They are true …

Invariant natural killer T (iNKT) cells are a unique population of T lymphocytes, which lie at
the interface between the innate and adaptive immune systems, and are important …

Optical biosensor technology continues to be the method of choice for label‐free, real‐time
interaction analysis. But when it comes to improving the quality of the biosensor literature …

Natural killer T cells (NKTs) are an important part of the immune system. Since their
discovery in the 1990s, researchers have gained deeper insights into the physiology and …

Associated with the CD1d protein, KRN 7000, a potent synthetic α-galactosylceramide, is
known to activate the invariant NKT immune cells. This stimulation then leads to the …

Together with peptides, T lymphocytes respond to hydrophobic molecules, mostly lipids,
presented by the non‐classical CD 1 family (CD 1a–e). These molecules have evolved …

Introduction The undiminished need for more effective cancer treatments stimulates the
development of novel cancer immunotherapy candidates. The archetypical cancer …

Tolerance against self-antigens is regulated by a variety of cell types with immunoregulatory
properties, such as CD1d-restricted invariant natural killer T (iNKT) cells. In many …