Rheumatic heart disease (RHD) is an important and preventable cause of morbidity and
mortality among children and young adults in low-income and middle-income countries, as …

Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Background Evidence is urgently needed to support treatment decisions for children with
multisystem inflammatory syndrome (MIS-C) associated with severe acute respiratory …

Children were relatively spared during COVID-19 pandemic. However, the recently reported
hyperinflammatory syndrome with overlapping features of Kawasaki disease and toxic shock …

Importance Sudden cardiac death (SCD) is the most common mode of death in childhood
hypertrophic cardiomyopathy (HCM), but there is no validated algorithm to identify those at …

Importance The prevalence and characteristics of bicuspid aortic valve (BAV) are mainly
reported from selected cohorts. BAV is associated with aortopathy, but it is unclear if it …

Enlargement of the aorta is an important risk factor for aortic aneurysm and dissection, a
leading cause of morbidity in the developed world. Here we performed automated extraction …

Background Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory
condition associated with SARS-CoV-2 infection, has emerged as a serious illness in …

Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …

Aims Understanding the spectrum of disease, symptom burden and natural history are
essential for the management of children with hypertrophic cardiomyopathy (HCM). The …