Alterations on the immune system caused by omega-3 fatty acids have been described for
30 years. This family of polyunsaturated fatty acids exerts major alterations on the activation …

It is well-established that the nutritional deficiency or inadequacy can impair immune
functions. Growing evidence suggests that for certain nutrients increased intake above …

Background Existing meta-analyses on omega-3 polyunsaturated fatty acids and their anti-
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …

Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

Aging is associated with declined immune function, particularly T cell-mediated activity,
which contributes to increased morbidity and mortality from infectious disease and cancer in …

Obesity is associated with increased risk for infections and poor responses to vaccinations,
which may be due to compromised B cell function. However, there is limited information …

Cell polarization enables restriction of signalling into microdomains. Polarization of
lymphocytes following formation of a mature immunological synapse (IS) is essential for …

Polyunsaturated fatty acids (PUFA) are known to have numerous beneficial effects, owing to
their anti-inflammatory and antioxidant properties. From a metabolic standpoint, the …

Mitochondria has emerged as a critical ruler of metabolic reprogramming in immune
responses and inflammation. In the context of colitogenic T cells and IBD, there has been …

Abstract n-3 polyunsaturated fatty acids (PUFA) have been shown in many clinical studies to
attenuate inflammatory responses. Although inflammatory responses are orchestrated by a …