[HTML][HTML] Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation

F Naznin, K Toshinai, TMZ Waise… - The Journal of …, 2015 - ncbi.nlm.nih.gov
Ghrelin, a stomach-derived orexigenic peptide, transmits starvation signals to the
hypothalamus via the vagus afferent nerve. Peripheral administration of ghrelin does not …

Appetite-and weight-regulating neuroendocrine circuitry in hypothalamic obesity

HW Gan, M Cerbone, MT Dattani - Endocrine Reviews, 2024 - academic.oup.com
Since hypothalamic obesity (HyOb) was first described over 120 years ago by Joseph
Babinski and Alfred Fröhlich, advances in molecular genetic laboratory techniques have …

[HTML][HTML] The function of gastrointestinal hormones in obesity—implications for the regulation of energy intake

M Farhadipour, I Depoortere - Nutrients, 2021 - mdpi.com
The global burden of obesity and the challenges of prevention prompted researchers to
investigate the mechanisms that control food intake. Food ingestion triggers several …

The future role of gut hormones in the treatment of obesity

RC Troke, TM Tan, SR Bloom - Therapeutic advances in …, 2014 - journals.sagepub.com
The obesity pandemic presents a significant burden, both in terms of healthcare and
economic outcomes, and current medical therapies are inadequate to deal with this …

Brain accessibility delineates the central effects of circulating ghrelin

M Perello, A Cabral, MP Cornejo… - Journal of …, 2019 - Wiley Online Library
Ghrelin is a hormone produced in the gastrointestinal tract that acts via the growth hormone
secretagogue receptor. In the central nervous system, ghrelin signalling is able to recruit …

Circulating preprandial ghrelin to obestatin ratio is increased in human obesity

ZF Guo, X Zheng, YW Qin, JQ Hu… - The Journal of …, 2007 - academic.oup.com
Context: Obestatin, a sibling of ghrelin derived from preproghrelin, opposes ghrelin's effects
on food intake. Plasma obestatin profiles in relation to ghrelin have not been fully …

Effects of central infusion of ghrelin on food intake and plasma levels of growth hormone, luteinizing hormone, prolactin, and cortisol secretion in sheep

J Iqbal, Y Kurose, B Canny, IJ Clarke - Endocrinology, 2006 - academic.oup.com
Ghrelin is an endogenous ligand for the GH secretagogue/ghrelin receptor (GHS-R) and
stimulates feeding behavior and GH levels in rodents and humans. A preprandial increase …

[HTML][HTML] Endogenous ghrelin levels and perception of hunger: a systematic review and meta-analysis

KC Anderson, F Hasan, EE Grammer, S Kranz - Advances in Nutrition, 2023 - Elsevier
Background Ghrelin is an orexigenic hormone primarily released by the stomach and has
two isoforms: acylated (AG) and de-acylated (DAG), that appear to have different functions in …

Ghrelin increases hunger and food intake in patients with restricting-type anorexia nervosa: a pilot study

M Hotta, R Ohwada, T Akamizu, T Shibasaki… - Endocrine …, 2009 - jstage.jst.go.jp
ghrelin increases hunger sensation and food intake in various patients with appetite loss.
anorexia nervosa (an) begins with psychological stress-induced anorexia and some patients …

Smell–taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions

F Fernández-Aranda, Z Agüera, JC Fernández-García… - Endocrine, 2016 - Springer
The objective of this study is to analyze differences in smell–taste capacity between females
in extreme weight/eating conditions (EWC) and (2) to explore the interaction between …