[HTML][HTML] The emerging roles and functions of circular RNAs and their generation

CY Yu, HC Kuo - Journal of biomedical science, 2019 - Springer
Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …

Lung cancer cells and their sensitivity/resistance to cisplatin chemotherapy: Role of microRNAs and upstream mediators

M Ashrafizadeh, A Zarrabi, K Hushmandi, F Hashemi… - Cellular signalling, 2021 - Elsevier
Cisplatin (CP) is a well-known chemotherapeutic agent with excellent clinical effects. The
anti-tumor activity of CP has been demonstrated in different cancers such as breast, cervical …

[HTML][HTML] CircRNA circRNA_102171 promotes papillary thyroid cancer progression through modulating CTNNBIP1-dependent activation of β-catenin pathway

W Bi, J Huang, C Nie, B Liu, G He, J Han… - Journal of Experimental …, 2018 - Springer
Background As a type of recently discovered noncoding RNA, circular RNAs (circRNAs)
exert pivot biological functions in diverse cancers. However, the role of circRNA_102171 in …

[HTML][HTML] Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide …

C Ding, X Yi, X Chen, Z Wu, H You, X Chen… - Journal of Experimental …, 2021 - Springer
Background Temozolomide (TMZ) resistance limits its application in glioma. Exosome can
carry circular RNAs (circRNAs) to regulate drug resistance via sponging microRNAs …

Biological roles and mechanisms of circular RNA in human cancers

Q Tang, SS Hann - OncoTargets and therapy, 2020 - Taylor & Francis
Circular RNA (circRNA) is an intriguing class of RNA with covalently closed-loop structure
and is highly stable and conservative. As new members of the ncRNAs, the function …

[HTML][HTML] CircFAT1 sponges miR-375 to promote the expression of Yes-associated protein 1 in osteosarcoma cells

G Liu, K Huang, Z Jie, Y Wu, J Chen, Z Chen, X Fang… - Molecular Cancer, 2018 - Springer
Background There is an urgent need to identify new molecular targets for treatment of
osteosarcoma. Circular RNAs are a class of endogenous RNAs that are extensively found in …

[HTML][HTML] Identification of circRNA–miRNA–mRNA regulatory network in gastric cancer by analysis of microarray data

Y Guan, J Ma, W Song - Cancer cell international, 2019 - Springer
Background Evidence is increasingly indicating that circular RNAs (circRNAs) are closely
involved in tumorigenesis and cancer progression. However, the function of circRNAs in …

[HTML][HTML] Circular RNAs: new layer of complexity evading breast cancer heterogeneity

A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …

Circular RNA circ_0001649 acts as a prognostic biomarker and inhibits NSCLC progression via sponging miR-331-3p and miR-338-5p

T Liu, Z Song, Y Gai - Biochemical and biophysical research …, 2018 - Elsevier
Accumulating evidence documented the key functions of circular RNAs (circRNAs) in
various malignancies. However, the study regarding the involvement of circRNAs in non …

[PDF][PDF] RETRACTED: circular RNA profiling reveals exosomal circ_0006156 as a novel biomarker in papillary thyroid cancer

G Wu, W Zhou, X Pan, Z Sun, Y Sun, H Xu, P Shi… - … Therapy-Nucleic Acids, 2020 - cell.com
Circular RNAs (circRNAs) are a class of noncoding RNAs that are broadly expressed in
various biological cells and function in regulating gene expression. However, the molecular …