In this review, we describe the laboratory implementation of Infinium® whole genome
genotyping (WGG) technology for whole genome association studies and copy number …

In the microarray format of the minisequencing method multiple oligonucleotide primers
immobilised on a glass surface are extended with fluorescent ddNTPs using a DNA …

Materials with tailored surface properties are useful for diverse applications, in particular for
adsorption and/or covalent immobilization of various biomolecules such as nucleic acids …

Here, we present a novel method for SNP genotyping based on protease-mediated allele-
specific primer extension (PrASE), where the two allele-specific extension primers only differ …

BACKGROUND: In the Netherlands, 500,000 blood donors are active. Blood of all donors is
currently typed serologically for ABO, the Rh phenotype, and K. Only a subset of donors is …

We report a new approach for electrochemical quantification of single-nucleotide
polymorphisms (SNPs) using nanoparticle probes. The principle is based on DNA …

Motivation As the volume of next-generation sequencing (NGS) data increases, faster
algorithms become necessary. Although speeding up individual components of a sequence …

Background Arrayed primer extension (APEX) is a microarray-based rapid minisequencing
methodology that may have utility in'personalized medicine'applications that involve genetic …

Background Whole genome amplification (WGA) promises to eliminate practical molecular
genetic analysis limitations associated with genomic DNA (gDNA) quantity. We evaluated …

US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents
US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents …