According to recent systematic reviews, Modic changes are associated with low-back pain.
However, their pathophysiology remains largely unknown. A previous study of Northern …

US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents
US7045610B2 - Modified oligonucleotides for mismatch discrimination - Google Patents …

We have developed a robust microarray genotyping chip that will help advance studies in
genetic epidemiology. In population-based genetic association studies of complex disease …

For nearly a century, genetic analysis in Drosophila melanogaster has been a powerful tool
for analyzing gene function, yet Drosophila lacks the molecular genetic mapping tools that …

Light‐directed synthesis of high‐density microarrays is currently performed in the 3′→ 5′
direction due to constraints in existing synthesis chemistry. This results in the probes being …

The analysis of DNA variation (polymorphisms and mutations) on a genome-wide scale is
becoming both increasingly important and technically challenging. An integration of a …

Software systems and methods for predicting the melting temperature (Tm) and other
characteristics of oligonucle otides, including modified oligonucleotides. Modified oligo …

AlphaScreen technology allows the development of high-throughput homogeneous
proximity assays. In these assays, signal is generated when 680 nm laser light irradiates a …

A technique used to amplify the number of copies of a specific region of DNA, the
polymerase chain reaction (PCR) is at the forefront of the dramatic development of …

Single-nucleotide polymorphisms (SNPs) constitute the bulk of human genetic variation and
provide excellent markers to identify genetic factors contributing to complex disease …