Adverse health consequences of performance-enhancing drugs: an Endocrine Society scientific statement

HG Pope Jr, RI Wood, A Rogol, F Nyberg… - Endocrine …, 2014 - academic.oup.com
Despite the high prevalence of performance-enhancing drug (PED) use, media attention has
focused almost entirely on PED use by elite athletes to illicitly gain a competitive advantage …

Toxicity of triptolide and the molecular mechanisms involved

C Xi, S Peng, Z Wu, Q Zhou, J Zhou - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Triptolide (TP), a major active and toxic ingredient isolated from the traditional Chinese herb
Tripterygium wilfordii Hook f.(TWHF). A widespread application of TP raises the question on …

Neurotoxicity by synthetic androgen steroids: oxidative stress, apoptosis, and neuropathology: a review

C Pomara, M Neri, S Bello, C Fiore… - Current …, 2015 - ingentaconnect.com
Anabolic-androgenic steroids (AAS) are synthetic substances derived from testosterone that
are largely employed due to their trophic effect on muscle tissue of athletes at all levels …

Effects of exercise training on nitric oxide, blood pressure and antioxidant enzymes

Y Tsukiyama, T Ito, K Nagaoka, E Eguchi… - Journal of clinical …, 2017 - jstage.jst.go.jp
抄録 The relationship between exercise training and nitric oxide-related parameters was
examined in a cross-sectional study and an intervention study. A cross-sectional study using …

Synthetic androgens as designer supplements

J Felix Joseph, M Kristina Parr - Current neuropharmacology, 2015 - ingentaconnect.com
Anabolic androgenic steroids (AAS) are some of the most common performance enhancing
drugs (PED) among society. Despite the broad spectrum of adverse effects and legal …

Amelioration of nandrolone decanoate-induced testicular and sperm toxicity in rats by taurine: effects on steroidogenesis, redox and inflammatory cascades, and …

MAE Ahmed - Toxicology and applied pharmacology, 2015 - Elsevier
The wide abuse of the anabolic steroid nandrolone decanoate by athletes and adolescents
for enhancement of sporting performance and physical appearance may be associated with …

[HTML][HTML] Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: A literature review

M Salerno, O Cascio, G Bertozzi, F Sessa, A Messina… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Anabolic androgenic steroids (AAS) are some of the most common drugs used among
athletes, frequently in combination with resistance training, to improve physical performance …

Protection of Quercetin against Triptolide-induced apoptosis by suppressing oxidative stress in rat Leydig cells

J Hu, Q Yu, F Zhao, J Ji, Z Jiang, X Chen, P Gao… - Chemico-Biological …, 2015 - Elsevier
Triptolide (TP) is a diterpene triepoxide with variety biological activities, such as anti-
inflammatory, anti-cancerogenic, immunomodulatory and pro-apoptotic activities. However …

Luteinizing hormone signaling is involved in synchronization of Leydig cell's clock and is crucial for rhythm robustness of testosterone production

AZ Baburski, SA Andric, TS Kostic - Biology of Reproduction, 2019 - academic.oup.com
In mammals, circadian clock regulates concentration of many reproductive hormones
including testosterone. Previously, we characterized pattern of circadian transcription of core …

Effects of nandrolone stimulation on testosterone biosynthesis in leydig cells

C Pomara, R Barone… - Journal of Cellular …, 2016 - Wiley Online Library
Anabolic androgenic steroids (AAS) are among the drugs most used by athletes for
improving physical performance, as well as for aesthetic purposes. A number of papers have …